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https://olympias.lib.uoi.gr/jspui/handle/123456789/19152| Title: | Predictors and impact of losses to follow-up in an HIV-1 perinatal transmission cohort in Malawi |
| Institution and School/Department of submitter: | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής |
| Keywords: | DNA, Viral/analysis,*Disease Transmission, Infectious/prevention & control,Female,Follow-Up Studies,Gestational Age,HIV Antibodies/analysis,HIV Infections/epidemiology/*transmission/virology,HIV-1/genetics/immunology,Humans,Infant,Infant, Newborn,Malawi/epidemiology,Male,Predictive Value of Tests,Pregnancy,Pregnancy Complications, Infectious/epidemiology/virology,Prevalence,Retrospective Studies,Risk Factors,HIV- infected cohort of delivering women in urban Malawi were studied. The women,enrolled in an intervention trial including vaginal cleansing with chlorhexidine,at the time of delivery. Findings showed that of the 2156 infants born to HIV-,infected mothers, about 1359 (63.1%) had been diagnosed with HIV infection, 797,(36.9%) with undetermined status, 144 (6.7%) with missing status, and about 653,(30.3%) were never brought back for follow-up. The odds of HIV positivity,decreased in the determination of infectious status (P = 0.03) despite the,probability of additional transmission from breast-feeding. Late-coming and lost,children of less educated parents had similar birth weight (P = 0.50) and were,likely less to return. This was probably due to the fact that the fathers of the,lost children were farmers. Besides, infant birth weight, twins vs. singletons,,and maternal education were affiliated with significant variation in the observed,risk of perinatal transmission among HIV-positive infants. Thus, with regard to,the intervention trial, the LFU were approximately equal in both groups. There,was no evidence that the losses were unbalanced between arms in relation to the,predictors of transmission. |
| URI: | https://olympias.lib.uoi.gr/jspui/handle/123456789/19152 |
| ISSN: | 0300-5771 |
| Link: | http://www.ncbi.nlm.nih.gov/pubmed/10480709 http://ije.oxfordjournals.org/content/28/4/769.full.pdf |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| Ioannidis-1999-Predictors and impac.pdf | 209.62 kB | Adobe PDF | View/Open Request a copy |
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