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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Antoniadis, C. D. | en |
| dc.contributor.author | Blake, A. J. | en |
| dc.contributor.author | Hadjikakou, S. K. | en |
| dc.contributor.author | Hadjiliadis, N. | en |
| dc.contributor.author | Hubberstey, P. | en |
| dc.contributor.author | Schroder, M. | en |
| dc.contributor.author | Wilson, C. | en |
| dc.date.accessioned | 2015-11-24T16:48:02Z | - |
| dc.date.available | 2015-11-24T16:48:02Z | - |
| dc.identifier.issn | 0108-7681 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/9271 | - |
| dc.rights | Default Licence | - |
| dc.subject | crystal structure | en |
| dc.subject | polyiodide networks | en |
| dc.subject | iodine complex | en |
| dc.subject | template | en |
| dc.subject | bonds | en |
| dc.title | Structural characterization of selenium and selenium-diiodine analogues of the antithyroid drug 6-n-propyl-2-thiouracil and its alkyl derivatives | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.primary | Doi 10.1107/S0108768106011426 | - |
| heal.identifier.secondary | <Go to ISI>://000238996600007 | - |
| heal.identifier.secondary | http://journals.iucr.org/b/issues/2006/04/00/so5003/so5003.pdf | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας | el |
| heal.publicationDate | 2006 | - |
| heal.abstract | The structures of four selenium analogues of the antithyroid drug 6-n-propyl-2-thiouracil [systematic name: 2,3-dihydro-6n-propyl-2-thioxopyrimidin-4(1H)-one], namely 6-methyl-2-selenouracil, C5H6N2OSe (1), 6-ethyl-2-selenouracil, C6H8N2OSe (2), 6-n-propyl-2-selenouracil, C7H10N2OSe (3), and 6-isopropyl-2-selenouracil, C7H10N2OSe (4), are described, along with that of the dichloromethane monosolvate of 6-isopropyl-2-selenouracil, C7H10N2OSe (.) CH2Cl2 (4 (.) CH2Cl2). The extended structure of (1) is a two-dimensional sheet of topology 6(3) with a brick-wall architecture. The extended structures of (2) and (4) are analogous, being based on a chain of eight-membered R-8(6)(32) hydrogen-bonded rings. In (3) and (4(.)CH(2)Cl(2)), R-2(2)(8) hydrogen bonding links molecules into chains. 6-n-Propyl-2-selenouracil(.)I(2), (C7H10N2OSeI2)-I-. (7), is a charge-transfer complex with a 'spoke' structure, the extended structure of which is based on a linear chain formed principally by intermolecular N-H O-... hydrogen bonds. Re-crystallization of 6-methyl-2-selenouracil or (7) from acetone gave crystals of the diselenides [N-(6'-ethyl-4'-pyrimidone)(6-ethyl-2-selenouracil) (2)(Se-Se)](.)2H(2)O (9(.)2H(2)O) or [N-(6'-n-propyl-4'-pyrimidone)(6-n-propyl-2-selenouracil)(2)(Se-Se)] (10), respectively: these have similar extended chain structures formed via N-H (...) O and C-H (...) O hydrogen bonds, stacked to give two-dimensional sheets. Re-crystallization of (7) from methanol/acetonitrile led via deselenation to the formation of crystals of 6-n-propyl-2-uracil (11), in which six symmetry-related molecules combine to form a six-membered R-6(6)(24) hydrogen-bonded ring, with each pair of molecules linked by an R-2(2)(8) motif. | en |
| heal.publisher | Blackwell | en |
| heal.journalName | Acta Crystallographica Section B-Structural Science | en |
| heal.journalType | peer reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά). ΧΗΜ | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Antoniadis-2006-Structural character.pdf | 777.53 kB | Adobe PDF | View/Open |
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