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dc.contributor.authorCharalampidis, P. S.en
dc.contributor.authorVeltsistas, P.en
dc.contributor.authorKarkabounas, S.en
dc.contributor.authorEvangelou, A.en
dc.date.accessioned2015-11-24T16:53:15Z-
dc.date.available2015-11-24T16:53:15Z-
dc.identifier.issn0223-5234-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/9992-
dc.rightsDefault Licence-
dc.subjectoxidative stressen
dc.subjectantioxidant capacityen
dc.subjectchromium peroxideen
dc.subjectspectrophotometryen
dc.subjectalpha-tocopherolen
dc.subjectascorbateen
dc.subjectoxidative stressen
dc.subjectfree-radicalsen
dc.subjectcyclic voltammetryen
dc.subjectreperfusion injuryen
dc.subjectiron-metabolismen
dc.subjectcoenzyme-qen
dc.subjectdiseaseen
dc.subjectenzymesen
dc.subjectplasmaen
dc.titleBlue CrO(5) assay: A novel spectrophotometric method for the evaluation of the antioxidant and oxidant capacity of various biological substancesen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primaryDOI 10.1016/j.ejmech.2009.05.007-
heal.identifier.secondary<Go to ISI>://000269398900043-
heal.identifier.secondaryhttp://ac.els-cdn.com/S0223523409003006/1-s2.0-S0223523409003006-main.pdf?_tid=1e006b478437397bdac3a2772ebbfb98&acdnat=1335451906_123a5cc629e8e9cd12b5422c8d39c008-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείαςel
heal.publicationDate2009-
heal.abstractOxidative stress plays a pivotal role in the ageing process and in the pathogenesis of numerable diseases. The quantification of the phenomenon is of paramount importance. in the present study, we introduce a novel and simple assay, the Blue CrO(5) assay, for the evaluation of the oxidant and antioxidant capacity of various biological samples and known antioxidants. Chromium peroxide (CrO(5)) is produced by ammonium dichromate in an acidic environment in the presence of H(2)O(2). it is a deep blue potent oxidant compound, miscible and relatively stable in polar organic solvents, that can be easily measured by spectrophotometry. Its reduction by known antioxidants, both water- and lipid-soluble (ascorbate and alpha-tocopherol, respectively, in this study), detected spectrophotometrically as a decrease in the absorption and depicted in EPR spectra, can act as a measure of the antioxidant capacity of a certain compound. The assay displays significant sensitivity, stability, linearity, specificity and repeatability. (C) 2009 Elsevier Masson SAS. All rights reserved.en
heal.journalNameEur J Med Chemen
heal.journalTypepeer reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά). ΧΗΜ

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