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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kovala-Demertzi, D. | en |
dc.contributor.author | Demertzis, M. A. | en |
dc.contributor.author | Varagi, V. | en |
dc.contributor.author | Papageorgiou, A. | en |
dc.contributor.author | Mourelatos, D. | en |
dc.contributor.author | Mioglou, E. | en |
dc.contributor.author | Iakovidou, Z. | en |
dc.contributor.author | Kotsis, A. | en |
dc.date.accessioned | 2015-11-24T16:51:40Z | - |
dc.date.available | 2015-11-24T16:51:40Z | - |
dc.identifier.issn | 0009-3157 | - |
dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/9766 | - |
dc.rights | Default Licence | - |
dc.subject | sister chromatid exchanges | en |
dc.subject | cell kinetics | en |
dc.subject | platinum(ii) and palladium(ii) complexes | en |
dc.subject | pyridine-2-carboxyaldehyde thiosemicarbazone | en |
dc.subject | antileukemic activity | en |
dc.subject | chromatid exchange assay | en |
dc.subject | vivo antitumor-activity | en |
dc.subject | spectral properties | en |
dc.subject | in-vitro | en |
dc.subject | 2-acetylpyridine | en |
dc.subject | thiosemicarbazones | en |
dc.subject | prediction | en |
dc.subject | antifungal | en |
dc.subject | invivo | en |
dc.title | Antineoplastic and cytogenetic effects of platinum(II) and palladium(II) complexes with pyridine-2-carboxyaldehyde-thiosemicarbazone | en |
heal.type | journalArticle | - |
heal.type.en | Journal article | en |
heal.type.el | Άρθρο Περιοδικού | el |
heal.identifier.secondary | <Go to ISI>://000076569400009 | - |
heal.identifier.secondary | http://content.karger.com/ProdukteDB/produkte.asp?doi=10.1159/000007154 | - |
heal.language | en | - |
heal.access | campus | - |
heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας | el |
heal.publicationDate | 1998 | - |
heal.abstract | The effect of six novel complexes of Pt(II) and Pd(II) with pyridine-2-carboxyaldehyde thiosemicarbazone (HPyTsc) on sister chromatid exchange rate and human lymphocyte proliferation kinetic was studied. Also, the effect of Pt(II) and Pd(II) complexes against leukemia P388 was investigated. Among these compounds, the most effective in inducing cytogenetic and antineoplastic effects are the complexes [Pd(PyTsc)(2)] and [Pt(PyTsc)(2)]. Next in order of magnitude in inducing antineoplastic and cytogenetic effects is the compound [Pt(HPyTsc)(2)]Cl-2 while the rest, i.e. [Pd(PyTsc)Cl], HPyTsc, [Pd(HPyTsc)(2)]Cl-2, and [Pt(PyTsc)Cl], show marginal cytogenetic and antineoplastic effects. | en |
heal.journalName | Chemotherapy | en |
heal.journalType | peer reviewed | - |
heal.fullTextAvailability | TRUE | - |
Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά). ΧΗΜ |
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