Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/9451
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dc.contributor.authorXanthopoulou, M. N.en
dc.contributor.authorHadjikakou, S. K.en
dc.contributor.authorHadjiliadis, N.en
dc.contributor.authorSchΓΌrmann, M.en
dc.contributor.authorJurkschat, K.en
dc.contributor.authorBinolis, J.en
dc.contributor.authorKarkabounas, S.en
dc.contributor.authorCharalabopoulos, K.en
dc.date.accessioned2015-11-24T16:49:14Z-
dc.date.available2015-11-24T16:49:14Z-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/9451-
dc.rightsDefault Licence-
dc.subjecttriphenyltin(IV) compound, S ligands-heterocyclic thioamides, mercaptonicotinic acid, crystal structuresen
dc.titleSynthesis of a novel triphenyltin(IV) derivative of 2-mercaptonicotinic acid with strong cytotoxicity in vitroen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείαςel
heal.publicationDate2003-
heal.abstractA novel triphenyltin(IV) derivative of 2-mercaptonicotinic acid (Hzmna) of formula {[(C6Hs)3Sn]E(mna)"™[(CH3)2CO]} (1) has been synthesized and characterized by elemental analysis and 13C-NMR, and FT-IR spectroscopic techniques. The crystal structure of complex (1) has been determined by single crystal X-ray diffraction analysis at 173(1) K. Compound (1) contains two triphenyltin moieties linked by a doubly de-protonated 2,mercaptonicotinic acid (HEmna). It is an example of a pentacoordinated Ph3SnXY system with an axial-equatorial arrangement of the phenyl groups at Sn(1). Compound (1), exhibits potent, in vitro, cytotoxicity against sarcoma cancer cells (mesenchymal tissue) from the Wistar rat, polycyclic aromatic hydrocarbons (PAH, benzo[a]pyrene) carcinogenesis.en
heal.journalNameBioinorganic Chemistry & Applicationsen
heal.journalTypepeer reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά). ΧΗΜ

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