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https://olympias.lib.uoi.gr/jspui/handle/123456789/9409Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Myari, A. | en |
| dc.contributor.author | Hadjiliadis, N. | en |
| dc.contributor.author | Garoufis, A. | en |
| dc.date.accessioned | 2015-11-24T16:49:00Z | - |
| dc.date.available | 2015-11-24T16:49:00Z | - |
| dc.identifier.issn | 0162-0134 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/9409 | - |
| dc.rights | Default Licence | - |
| dc.subject | metallopeptides | en |
| dc.subject | oligonucleotide | en |
| dc.subject | ru(ii) complexes | en |
| dc.subject | chimeric complexes | en |
| dc.subject | minor-groove-binding | en |
| dc.subject | DNA-binding | en |
| dc.subject | crystal-structure | en |
| dc.subject | d(g-g-a-a-t-t-c-c) duplex | en |
| dc.subject | restriction-endonuclease | en |
| dc.subject | peptide complexes | en |
| dc.subject | aqueous-solution | en |
| dc.subject | cognate DNA | en |
| dc.subject | sequence | en |
| dc.subject | recognition | en |
| dc.title | Synthesis and characterization of the diastereomers Lambda- and Delta-[Ru(bpy)(2)(m-bpy-L-Arg-Gly-L-Asn-L-Ala-L-His-L-Glu-L-Arg)]Cl-2 H-1 NMR studies on their interactions with the deoxynucleotide duplex d[(5 '-GCGCTTAAGCGC-3 ')(2)] and d[(5 '-CGCGATCGCG-3 ')(2)] | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.primary | DOI 10.1016/j.jinorgbio.2004.11.010 | - |
| heal.identifier.secondary | <Go to ISI>://000226392400031 | - |
| heal.identifier.secondary | http://ac.els-cdn.com/S0162013404003770/1-s2.0-S0162013404003770-main.pdf?_tid=31487d0b6a346bb7ac583735d0df7ef6&acdnat=1333029302_0b09d3aa0b85cc6384a7f320ad89a3c1 | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας | el |
| heal.publicationDate | 2005 | - |
| heal.abstract | The diastereomeric complexes Lambda- and Delta-[Ru(bpy)(2)(M-bpy-7p)]Cl-2, (bpy = 2,2'-bipyridine, m-bpy-7p = 4-methyl-4'-Arg-Gly-Asn-Ala-His-Glu-Arg-CONH2-2,2'-bipyridine) were synthesized and characterized and their binding properties to the deoxynucleotide duplexes d(5'-CGCGATCGCG-3')(2) and d(5'-GCGCTTAAGCGC-3')(2) were studied by means of H-1 NMR spectroscopy. 7p is part of the recognition loop of the restriction endonuclease MunI, a type II restriction enzyme from Mycoplasma unidentified which recognizes the palindromic hexanucleotide sequence C/AATTG and cleaves it as indicated by the slash. The A-isomer binds to the terminal CG/GC major groove of d(CGCGATCGCG)(2) decanucleotide, whereas the A-isomer approaches the GCT/CGA sequence. On the other hand, weak binding of the Delta-isomer to the end of d(GCGCTTAAGCGC)(2) into two different orientations is observed. In the case of the A-isomer, the bpy ligand(s) are located into the major groove of the central TT/AA sequence. The role of appended peptide sequences in sequence selectivity binding to DNA is being addressed. (C) 2004 Elsevier Inc. All rights reserved. | en |
| heal.publisher | Elsevier | en |
| heal.journalName | J Inorg Biochem | en |
| heal.journalType | peer reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά). ΧΗΜ | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Myari-2005-Synthesis and charac.pdf | 330.92 kB | Adobe PDF | View/Open Request a copy |
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