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https://olympias.lib.uoi.gr/jspui/handle/123456789/8991Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Pontiki, E. A. | en |
| dc.contributor.author | Hadjipavlou-Litina, D. J. | en |
| dc.contributor.author | Demertzis, A. M. | en |
| dc.contributor.author | Hadjidakis, I. | en |
| dc.contributor.author | Kovala-Demertzi, D. | en |
| dc.date.accessioned | 2015-11-24T16:45:50Z | - |
| dc.date.available | 2015-11-24T16:45:50Z | - |
| dc.identifier.issn | 1475-6366 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/8991 | - |
| dc.rights | Default Licence | - |
| dc.subject | quantitative structure activity relationships | en |
| dc.subject | (s)-phenylpiperidines | en |
| dc.subject | dopamine antagonists | en |
| dc.subject | qsar | en |
| dc.subject | receptors | en |
| dc.title | Quantitative structure activity relationships (QSAR) of substituded (S)-phenylpiperidines as preferential dopamine autoreceptor antagonists | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.primary | Doi 10.1080/14756360400002023 | - |
| heal.identifier.secondary | <Go to ISI>://000227432900002 | - |
| heal.identifier.secondary | http://informahealthcare.com/doi/abs/10.1080/14756360400002023 | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας | el |
| heal.publicationDate | 2005 | - |
| heal.abstract | A QSAR analysis for substituted (S)-phenylpiperidines as dopamine (DA) antagonists is described. The studied derivatives differ at the nitrogen substitutent (R) and at the substitutents (X) of the phenyl-ring. The analysis was done using the C-QSAR suite program (Biobyte) through the Internet. Clog P, CMR, M-Vol, B-1 and L (the Verloop's sterimol parameters for the substitutents) were used as parameters. In all the three studied cases clog P plays a significant part in the QSAR of DA antagonists, followed by the steric factors. In one case the electronic effect contributes significantly. | en |
| heal.journalName | J Enzyme Inhib Med Chem | en |
| heal.journalType | peer reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά). ΧΗΜ | |
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