Please use this identifier to cite or link to this item:
https://olympias.lib.uoi.gr/jspui/handle/123456789/8882Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Kovala-Demertzi, D. | en |
| dc.contributor.author | Demertzis, M. A. | en |
| dc.contributor.author | Miller, J. R. | en |
| dc.contributor.author | Papadopoulou, C. | en |
| dc.contributor.author | Dodorou, C. | en |
| dc.contributor.author | Filousis, G. | en |
| dc.date.accessioned | 2015-11-24T16:45:05Z | - |
| dc.date.available | 2015-11-24T16:45:05Z | - |
| dc.identifier.issn | 0162-0134 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/8882 | - |
| dc.rights | Default Licence | - |
| dc.subject | platinum(ii) complex | en |
| dc.subject | thiosemicarbazonato complex | en |
| dc.subject | crystal structure | en |
| dc.subject | spectroscopic study | en |
| dc.subject | antibacterial, antifungal, antineoplastic activity | en |
| dc.subject | p-isopropylbenzaldehyde thiosemicarbazone | en |
| dc.subject | palladium(ii) complexes | en |
| dc.subject | cytotoxic activity | en |
| dc.subject | biological-activity | en |
| dc.subject | DNA-binding | en |
| dc.subject | in-vitro | en |
| dc.subject | 3-hexamethyleneiminylthiosemicarbazones | en |
| dc.subject | copper(ii) | en |
| dc.subject | compound | en |
| dc.subject | ligand | en |
| dc.title | Platinum(II) complexes with 2-acetyl pyridine thiosemicarbazone - Synthesis, crystal structure, spectral properties, antimicrobial and antitumour activity | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.secondary | <Go to ISI>://000171350800003 | - |
| heal.identifier.secondary | http://ac.els-cdn.com/S0162013401002240/1-s2.0-S0162013401002240-main.pdf?_tid=8f6117edb92ecc8694c53d3a0f7de56b&acdnat=1333028678_cc18c53575f1ea29de46d28f0a904100 | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας | el |
| heal.publicationDate | 2001 | - |
| heal.abstract | An interesting series of new platinum complexes has been synthesized by the reaction of Na(2)ptCl(4) with 2-acetyl pyridine thiosemicarbazone, HAcTsc. The new complexes, [Pt(AcTsc)CI], [Pt(HAcTsc),]Cl-2 and [Pt(AcTsc)(2)], have been characterized by elemental analyses and spectroscopic studies. The crystal structure of the complex [Pt(AcTsc)CI] has been solved by single-crystal X-ray diffraction. The anion of HAcTsc coordinates in a planar conformation to the central platinum(II) through the pyridyl N, azomethine N and thiolato S atoms. Double intermolecular hydrogen bonds (NH-CI), pi-pi and weak Pt-Pt and Pt-pi contacts lead to aggregation and to a two-dimensional supramolecular assembly. The antibacterial and antifungal effect of the novel platinum(II) complexes and the related palladium(fl) complexes, [Pd(AcTsc)CI], [d(HAcTsc),]Cl, and [Pd(AcTsc),], were studied in vitro. The complexes were found to have a completely lethal effect on Gram+ bacteria, while the same complexes showed no bactericidal effect on Gram- bacteria. Additionally, the complexes [Pt(AcTsc),] and [Pd(AcTsc),] showed effective antifungal activity towards yeast. Among these compounds [33], the most effective in inducing antitumour and cytogenetic effects are the complexes [Pt(AcTsc)(2)] and [Pd(AcTsc)(2)] while the rest, display marginal cytogenetic and antitumour effects. (C) 2001 Elsevier Science BY All rights reserved. | en |
| heal.journalName | J Inorg Biochem | en |
| heal.journalType | peer reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά). ΧΗΜ | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Kovala-Demertzi-2001-Platinum(II) complex.pdf | 623.21 kB | Adobe PDF | View/Open Request a copy |
This item is licensed under a Creative Commons License
