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dc.contributor.authorWiecek, J.en
dc.contributor.authorKovala-Demertzi, D.en
dc.contributor.authorCiunik, Z.en
dc.contributor.authorWietrzyk, J.en
dc.contributor.authorZervou, M.en
dc.contributor.authorDemertzis, M. A.en
dc.date.accessioned2015-11-24T16:43:35Z-
dc.date.available2015-11-24T16:43:35Z-
dc.identifier.issn1565-3633-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/8717-
dc.rightsDefault Licence-
dc.subjectpalladium(ii) complexesen
dc.subject2-acetyl pyridineen
dc.subjectdiorganotin derivativesen
dc.subjectplatinum(ii) complexesen
dc.subjectmolecular-structuresen
dc.subjectspectral propertiesen
dc.subjectdrug interactionsen
dc.subjectmetal-complexesen
dc.subject1st complexesen
dc.subjectthiosemicarbazoneen
dc.titleOrganotin Compound Derived from 3-Hydroxy-2-formylpyridine Semicarbazone: Synthesis, Crystal Structure, and Antiproliferative Activityen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primaryDoi 10.1155/2010/718606-
heal.identifier.secondary<Go to ISI>://000278144700001-
heal.identifier.secondaryhttp://downloads.hindawi.com/journals/bca/2010/718606.pdf-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείαςel
heal.publicationDate2010-
heal.abstractThe novel diphenyltin(IV) compound [Ph(2)(HyFoSc)Sn] (2), where H(2)HyFoSc (1) is 3-hydroxy-2-formylpyridine semicarbazone, was prepared and characterized by vibrational and NMR ((1)H, (13)C) spectroscopy. The structure of [Ph(2)(HyFoSc)Sn] was confirmed by single-crystal X-ray crystallography. The doubly deprotonated ligand is coordinated to the tin atom through the enolic-oxygen, the azomethine-nitrogen, and phenolic-oxygen, and so acts as an anionic tridentate ligand with the ONO donors. Two carbon atoms complete the fivefold coordination at the tin( IV) center. Intermolecular hydrogen bonding, C-H -> pi, and pi -> pi interactions combine to stabilize the crystal structure. Compounds 1 and 2 have been evaluated for antiproliferative activity in vitro against the cells of three human tumor cell lines: MCF-7 (human breast cancer cell line), T24 (bladder cancer cell line), A549 (nonsmall cell lung carcinoma), and a mouse fibroblast L-929 cancer cell line.en
heal.journalNameBioinorg Chem Applen
heal.journalTypepeer reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά). ΧΗΜ

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