Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/8394
Full metadata record
DC FieldValueLanguage
dc.contributor.authorYao, D. C.en
dc.contributor.authorVlessidis, A. G.en
dc.contributor.authorEvmiridis, N. P.en
dc.contributor.authorEvangelou, A.en
dc.contributor.authorKarkabounas, S.en
dc.contributor.authorTsampalas, S.en
dc.date.accessioned2015-11-24T16:41:16Z-
dc.date.available2015-11-24T16:41:16Z-
dc.identifier.issn0003-2670-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/8394-
dc.rightsDefault Licence-
dc.subjectnitric oxideen
dc.subjectin vivo monitoringen
dc.subjectmicrodialysis samplingen
dc.subjectchemiluminescenceen
dc.subjectviagraen
dc.subjectflow-injectionen
dc.subjectrelaxing factoren
dc.subjectl-arginineen
dc.subjectnoen
dc.subjectsuperoxideen
dc.subjectmechanismen
dc.subjectsynthaseen
dc.subjectsystemen
dc.subjectsensoren
dc.subjectassayen
dc.titleLuminol chemiluminescense reaction: a new method for monitoring nitric oxide in vivoen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primaryDoi 10.1016/S0003-2670(02)00070-3-
heal.identifier.secondary<Go to ISI>://000175752500003-
heal.identifier.secondaryhttp://ac.els-cdn.com/S0003267002000703/1-s2.0-S0003267002000703-main.pdf?_tid=98fcc02a-356a-11e3-a246-00000aacb35e&acdnat=1381821950_6a27f4e8a15c85565b6f13db7c65265d-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείαςel
heal.publicationDate2002-
heal.abstractA new method employing a combination of microdialysis sampling and chemiluminescence (CL) detection was developed to monitor nitric oxide (NO) in vivo. A special probe was designed with an interference-free membrane to achieve very high selectivity for NO. High sensitivity was achieved by optimizing the working system and improving the NO sampling time. This system was used in vivo to monitor blood and brain tissue in rats and rabbits. The system is sensitive enough to detect variations of NO formation under different physiological states. The linear valid range of NO determination is 5 nM to 1 muM, with a 3sigma detection limit of I nM; real NO concentrations in test animals used in this work were found to be in the range of 1-5 nM or even less. Finally, the effects of body temperature, NO donors, Viagra, NO activators, NO cofactors and NO interference (such as O-2) were investigated carefully in different physiological situations. (C) 2002 Elsevier Science B.V. All rights reserved.en
heal.publisherElsevier Massonen
heal.journalNameAnalytica Chimica Actaen
heal.journalTypepeer reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά). ΧΗΜ

Files in This Item:
File Description SizeFormat 
Yao-2002-Luminol chemilumines.pdf119.54 kBAdobe PDFView/Open    Request a copy


This item is licensed under a Creative Commons License Creative Commons