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dc.contributor.authorManataki, A. D.en
dc.contributor.authorTselepis, A. D.en
dc.contributor.authorGlantzounis, G. K.en
dc.contributor.authorArnaoutoglou, H. M.en
dc.contributor.authorTsimoyiannis, E. C.en
dc.contributor.authorStavropoulos, N. E.en
dc.date.accessioned2015-11-24T16:41:05Z-
dc.date.available2015-11-24T16:41:05Z-
dc.identifier.issn0930-2794-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/8361-
dc.rightsDefault Licence-
dc.subjectlaparoscopic surgeryen
dc.subjectlipid peroxidationen
dc.subjectpropofolen
dc.subjectpneumoperitoneumen
dc.subjectoxidative stressen
dc.subjectantioxidanten
dc.subjectischemiaen
dc.subject2,6-diisopropylphenolen
dc.subjectanesthesiaen
dc.subjectscavengeren
dc.subjectincreaseen
dc.subjectplasmaen
dc.subjectageen
dc.titleLipid peroxidation and the use of emulsified propofol in laparoscopic surgeryen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondary<Go to ISI>://000170773900010-
heal.identifier.secondaryhttp://www.springerlink.com/content/hyuh783e6gl8690u/fulltext.pdf-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείαςel
heal.publicationDate2001-
heal.abstractBackground: Free radical-induced lipid peroxidation associated with a decrease of antioxidant capacity in plasma is observed after the deflation of the pneumoperitoneum in laparoscopic surgery. In this study, we evaluated the effect of the continuous administration of lipid peroxidation derivatives on emulsified propofol. Methods: Two groups of 20 patients each who underwent laparoscopic surgery were studied prospectively. Maintenance of anesthesia was achieved with 66% nitrous oxide and either isoflurane or continuous propofol administration. The level of thiobarbituric acid-reactive substances (TBARS) in the plasma was determined as a measure of free radicals before and after surgery. Results: Ten patients in the propofol group had reduced TBARS. as compared to only one in the isoflurane group (p = 0.003). There was a statistically significant difference in age between the patients with reduced TBARS and those without reduced TBARS (P = 0.009) in the propofol group. Conclusions: Anesthesia with continuous propofol infusion in laparoscopic surgery has a significant scavenging action on the formation of free radicals and exerts its greatest antioxidant effect in patients greater than or equal to 48 years of age.en
heal.journalNameSurgical Endoscopy-Ultrasound and Interventional Techniquesen
heal.journalTypepeer reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά). ΧΗΜ

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