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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Psarropoulou, C. | en |
| dc.contributor.author | Avoli, M. | en |
| dc.date.accessioned | 2015-11-24T16:35:14Z | - |
| dc.date.available | 2015-11-24T16:35:14Z | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/7918 | - |
| dc.rights | Default Licence | - |
| dc.title | Subthreshold membrane-potential oscillations in immature rat CA3 hippocampal neurones. | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών και Τεχνολογιών. Τμήμα Βιολογικών Εφαρμογών και Τεχνολογιών | el |
| heal.publicationDate | 1995 | - |
| heal.abstract | Subthreshold membrane potential oscillations (MPOs) were recorded intracellularly in 31 of 43 (>70%) immature CA3 hippocampal neurones (from 3-17 days postnatally). MPOs (3-5 mV, 3-15 Hz) occurred at resting membrane potential (RMP) in 20 of 31 neurones, or following depolarization (11 of 31 neurones); with sufficient depolarization spontaneous action potentials (APs) were generated from the positive-going phase of MPOs. In all cells, MPOs were blocked by steady membrane hyperpolarization. Tetrodotoxin abolished MPOs (n = 4); Co(2+) markedly reduced them (n = 3), and tetraethylammonium, added in the presence of TTX, revealed lower frequency oscillatory activity (n = 2). We conclude that subthreshold MPOs in immature hippocampus, possibly linked to theta rhythm generation and memory acquisition, depend on voltage-dependent Na+ electrogenesis and they might be additionally controlled by Ca(2+) and K+ conductances. | en |
| heal.journalName | Neuroreport | en |
| heal.journalType | peer reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Psarropoulou-1995-Subthreshold membran.pdf | 375.82 kB | Adobe PDF | View/Open Request a copy |
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