Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/7632
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dc.contributor.authorCarroll, Johnen
dc.contributor.authorFitzHarris, Gregen
dc.contributor.authorMarangos, Petrosen
dc.contributor.authorHalet, Guillaumeen
dc.date.accessioned2015-11-24T16:33:14Z-
dc.date.available2015-11-24T16:33:14Z-
dc.identifier.issn0301-2115-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/7632-
dc.rightsDefault Licence-
dc.subjectOocyteen
dc.subjectEggen
dc.subjectCa2+en
dc.subjectInositolen
dc.subjectFertilisationen
dc.titleCa2+ signalling and cortical re-organisation during the transition from meiosis to mitosis in mammalian oocytesen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primaryhttp://dx.doi.org/10.1016/j.ejogrb.2004.01.024-
heal.identifier.secondaryhttp://www.sciencedirect.com/science/article/pii/S030121150400020X-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών και Τεχνολογιών. Τμήμα Βιολογικών Εφαρμογών και Τεχνολογιώνel
heal.publicationDate2004-
heal.abstractIn mammals, the mature ovulated egg is arrested in metaphase II of the first meiotic division. The signal that triggers the transition from meiosis to mitosis is provided by the fertilising sperm and takes the form of a series of Ca2+ oscillations. The pattern of Ca2+ oscillations is imposed by maternal control mechanisms that ensure Ca2+ transients occur during M-phase of meiosis II and during the first mitotic division. The transition from meiosis to mitosis involves a major re-organisation. The unfertilised egg is polarised with the meiotic spindle located in the cortex of the animal pole and clusters of endoplasmic reticulum in the vegetal hemisphere. By the time of the first mitotic division some 20 h later the spindle has formed in the centre of the embryo and is surrounded by endoplasmic reticulum. These changes in organisation have implications for the inheritance of ER in meiotic and mitotic cell divisions and may reflect different roles and requirements for Ca2+ in meiosis and mitosis.en
heal.journalNameEuropean Journal of Obstetrics & Gynecology and Reproductive Biologyen
heal.journalTypepeer reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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