Please use this identifier to cite or link to this item:
https://olympias.lib.uoi.gr/jspui/handle/123456789/33113| Title: | Μοριακά μονοπάτια ρυθμιζόμενα από την πρωτεΐνη Drk στην μάθηση και την ανεξάρτητη της πρωτεϊνοσύνθεσης μνήμη στο Drosophila melanogaster Drk-mediated molecular pathways in learning and Protein Synthesis-Independent Memory (PSIM) in Drosophila melanogaster |
| Institution and School/Department of submitter: | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας University of Ioannina. School of Health Sciences |
| Keywords: | Μνήμη,Memory,Δροσόφιλα,Drosophila melanogaster,Ανεξάρτητη της πρωτεϊνοσύνθεσης μνήμη,Protein-synthesis independent memory,Οσφρητική εξαρτημενή μάθηση,Olfactory conditioning |
| URI: | https://olympias.lib.uoi.gr/jspui/handle/123456789/33113 http://dx.doi.org/10.26268/heal.uoi.12884 |
| Table of contents: | A. ΠΕΡΙΛΗΨΗ B. ABSTRACT C. INTRODUCTION 1. Learning and memory 1.1. Definition of memory 1.2. Types of memory 1.3. How do we study behavior? 1.4. Associative memory and the Pavlovian assay 2. Drosophila melanogaster 2.1. Drosophila in biomedical research 2.2. Life cycle 2.3. Genetic tools and molecular techniques 3. Mushroom Bodies-Center of olfactory learning and memory in Drosophila melanogaster 3.1. Anatomy 3.2 Function and role in learning and memory 4. Learning and memory in Drosophila 4.1. Memory phases in Drosophila 4.2. Anesthesia Resistant Memory (ARM) 4.3. ARM vs LTM 4.4. Distinction between ARM and MC-Elicited Memory 5. Molecular pathways involved in learning and memory 5.1. RAS/RAF/MAPK pathway 6. The protein Drk/GRB2 6.1. Role in learning and memory 6.2. Drk Reduction Selectively Affects PSIM D. AIM-IMPORTANCE OF PRESENT STUDY E. EXPERIMENTAL PROCEDURES 1. Drosophila cultures and strains 2. Behavioral assays 3. Western blotting 4. Phalloidin Staining and Confocal Microscopy 5. Statistical analysisTable of contents F. RESULTS A. Previous data from Skoulakis lab (unpublished data) B. Data from experiments conducted for this thesis 1. Behavioral part 2. Molecular part G. DISCUSSION H. APPENDIX I. REFERENCES |
| Appears in Collections: | Διατριβές Μεταπτυχιακής Έρευνας (Masters) - ΙΑΤ |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Μ.Ε. Αθανάσιος Μανώλης (2023).pdf | 2.56 MB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License
