Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/24690
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dc.contributor.authorAnagnostopoulos, P. V.en
dc.contributor.authorToumpoulis, I. K.en
dc.contributor.authorShepard, A. D.en
dc.contributor.authorDrossos, G. E.en
dc.contributor.authorTsatsoulis, A.en
dc.contributor.authorAnagnostopoulos, C. E.en
dc.date.accessioned2015-11-24T19:42:47Z-
dc.date.available2015-11-24T19:42:47Z-
dc.identifier.issn1401-7431-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/24690-
dc.rightsDefault Licence-
dc.subjectAdrenal Glands/*blood supply/*physiopathologyen
dc.subjectAdrenal Insufficiency/blood/etiology/*physiopathologyen
dc.subjectAdrenocorticotropic Hormone/blooden
dc.subjectAnimalsen
dc.subject*Aorta, Thoracicen
dc.subjectBalloon Occlusion/adverse effectsen
dc.subjectDisease Models, Animalen
dc.subjectHydrocortisone/blooden
dc.subject*Ischemia/etiologyen
dc.subjectPituitary-Adrenal System/*physiopathologyen
dc.subjectSwineen
dc.titleTemporary adrenal dysfunction with descending thoracic aortic occlusionen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1080/14017430701227754-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/17680513-
heal.identifier.secondaryhttp://informahealthcare.com/doi/abs/10.1080/14017430701227754-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2007-
heal.abstractBACKGROUND: We sought to determine whether descending thoracic aortic occlusion (DTAOC) induced ischemia results in adrenal dysfunction. METHODS: Eight pigs underwent DTAOC for 45 min. Six control pigs underwent a sham procedure. Serum cortisol and adrenocorticotropic hormone (ACTH) were measured at baseline, at the end of DTAOC, 30 and 60 min after restoration of flow, and 24 hours later. Statistical analysis was performed using repeated measures ANOVA and t-test. RESULTS: In the study group, cortisol levels decreased during DTAOC (p=0.048) and 30 min after flow restoration (p=0.004). In the control group there was no change in serum cortisol levels. In the study group the drop in serum cortisol was associated with an increase in ACTH levels during DTAOC (p=0.040) and 30 minutes after flow restoration (p=0.070). The increase in ACTH was also significant when compared to the controls during DTAOC (p=0.030) and 30 min after blood flow restoration (p=0.040). CONCLUSIONS: There is a transient period of adrenal dysfunction associated with DTAOC that results in stimulation of the pituitary-adrenal axis.en
heal.journalNameScand Cardiovasc Jen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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