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DC Field | Value | Language |
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dc.contributor.author | Vairaktaris, E. | en |
dc.contributor.author | Yapijakis, C. | en |
dc.contributor.author | Nkenke, E. | en |
dc.contributor.author | Vassiliou, S. | en |
dc.contributor.author | Vylliotis, A. | en |
dc.contributor.author | Nixon, A. M. | en |
dc.contributor.author | Derka, S. | en |
dc.contributor.author | Ragos, V. | en |
dc.contributor.author | Spyridonidou, S. | en |
dc.contributor.author | Tsigris, C. | en |
dc.contributor.author | Neukam, F. W. | en |
dc.contributor.author | Patsouris, E. | en |
dc.date.accessioned | 2015-11-24T19:42:38Z | - |
dc.date.available | 2015-11-24T19:42:38Z | - |
dc.identifier.issn | 0361-8609 | - |
dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/24670 | - |
dc.rights | Default Licence | - |
dc.subject | Adult | en |
dc.subject | Aged | en |
dc.subject | Aged, 80 and over | en |
dc.subject | Carboxypeptidase U/*genetics | en |
dc.subject | Carcinoma, Squamous Cell/*genetics | en |
dc.subject | Case-Control Studies | en |
dc.subject | Female | en |
dc.subject | Gene Frequency | en |
dc.subject | *Genetic Predisposition to Disease | en |
dc.subject | Germany | en |
dc.subject | Greece | en |
dc.subject | Homozygote | en |
dc.subject | Humans | en |
dc.subject | Male | en |
dc.subject | Middle Aged | en |
dc.subject | Mouth Neoplasms/*genetics | en |
dc.subject | Polymorphism, Single Nucleotide/*genetics | en |
dc.title | The 1040C/T polymorphism influencing thermal stability and activity of thrombin activatable fibrinolysis inhibitor is associated with risk for oral cancer | en |
heal.type | journalArticle | - |
heal.type.en | Journal article | en |
heal.type.el | Άρθρο Περιοδικού | el |
heal.identifier.primary | 10.1002/ajh.20985 | - |
heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/17636471 | - |
heal.identifier.secondary | http://onlinelibrary.wiley.com/store/10.1002/ajh.20985/asset/20985_ftp.pdf?v=1&t=h0atvxln&s=71caa113aec971d022dddc814abf1874ce031163 | - |
heal.language | en | - |
heal.access | campus | - |
heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
heal.publicationDate | 2007 | - |
heal.abstract | No studies thus far have investigated the contribution of thrombin activatable fibrinolysis inhibitor (TAFI) to oral oncogenesis. We studied the activity-related 1040C/T polymorphism in 150 patients with oral cancer and 138 healthy controls matched by age, gender, and ethnicity. The increased-activity T allele frequency was significantly reduced in patients compared with controls (28.7% vs. 37.0%, P < 0.05). T/T homozygotes had about half the probability of developing oral cancer (O.R. 0.39, 95%C.I. 0.13-1.14), while no significant difference was observed in C/T heterozygotes. The observed prophylactic effect of increased TAFI activity might result from reduction of plasmin and inhibition of extracellular matrix dissolution. | en |
heal.journalName | Am J Hematol | en |
heal.journalType | peer-reviewed | - |
heal.fullTextAvailability | TRUE | - |
Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ |
Files in This Item:
File | Description | Size | Format | |
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Vairaktaris-2007-The 1040C_T polymorp.pdf | 99.87 kB | Adobe PDF | View/Open Request a copy |
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