Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/24512
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dc.contributor.authorKioukia-Fougia, N.en
dc.contributor.authorAntoniou, K.en
dc.contributor.authorBekris, S.en
dc.contributor.authorLiapi, C.en
dc.contributor.authorChristofidis, I.en
dc.contributor.authorPapadopoulou-Daifoti, Z.en
dc.date.accessioned2015-11-24T19:41:37Z-
dc.date.available2015-11-24T19:41:37Z-
dc.identifier.issn0278-5846-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/24512-
dc.rightsDefault Licence-
dc.subjectAdrenocorticotropic Hormone/blooden
dc.subjectAnimalsen
dc.subjectBlood Glucose/*metabolismen
dc.subjectCold Temperatureen
dc.subjectHypothalamo-Hypophyseal System/metabolism/*physiopathologyen
dc.subjectMaleen
dc.subjectOrgan Sizeen
dc.subjectPituitary-Adrenal System/metabolism/*physiopathologyen
dc.subjectRatsen
dc.subjectRats, Sprague-Dawleyen
dc.subjectStress, Physiological/blood/*physiopathologyen
dc.subjectThymus Gland/metabolism/*physiopathologyen
dc.subjectThyroid Hormones/*blooden
dc.titleThe effects of stress exposure on the hypothalamic-pituitary-adrenal axis, thymus, thyroid hormones and glucose levelsen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/12369253-
heal.identifier.secondaryhttp://ac.els-cdn.com/S0278584601002974/1-s2.0-S0278584601002974-main.pdf?_tid=eef78a1a3b2c4de529392e2c329539cd&acdnat=1332925211_8021f7f601a61770e9fd627e36dbbf14-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2002-
heal.abstractIn the present study, an attempt was made to compare three stress models and their effects on the hypothalamic-pituitary-adrenal (HPA) axis, the thymus, the thyroid hormones and the glucose levels. The three different stress models were the chronic mild stress (CMS), the 14-day and the 1-day cold swim stress model. The CMS procedure caused a decrease in thymus weight and rendered no changes on glucose, the adrenocorticotropin hormone (ACTH) or the adrenals. Administration of imipramine (IMI) after the third week of CMS did not reverse the decrease in thymus weight. The 14-day cold swim stress doubled ACTH levels and the adrenal weight and reduced thymus weight, while total thyroxine (tT4), total triiodothyronine (tT3) and glucose levels were unaffected. IMI treatment restored the weights of the adrenal and thymus glands. One-day cold swim stress did not induce any statistically significant effect on the tested physiological parameters. The above findings indicate a distinct effect of the 14-day cold swim stress on HPA axis. Relative to CMS or the 14-day cold swim stress, no effect was induced by the 1-day cold swim stress. The IMI restoring effect, especially in the case of the 14-day cold swim stress, also suggests an association of antidepressant effect with the duration of drug treatment.en
heal.journalNameProg Neuropsychopharmacol Biol Psychiatryen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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