Please use this identifier to cite or link to this item:
https://olympias.lib.uoi.gr/jspui/handle/123456789/24507Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Kyriakides, Z. S. | en |
| dc.contributor.author | Manolis, A. G. | en |
| dc.contributor.author | Kolettis, T. M. | en |
| dc.date.accessioned | 2015-11-24T19:41:36Z | - |
| dc.date.available | 2015-11-24T19:41:36Z | - |
| dc.identifier.issn | 1874-1754 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/24507 | - |
| dc.rights | Default Licence | - |
| dc.subject | Animals | en |
| dc.subject | Coronary Circulation/*physiology | en |
| dc.subject | Heart/*physiopathology | en |
| dc.subject | Heart Conduction System/*physiopathology | en |
| dc.subject | Heart Failure/*physiopathology | en |
| dc.subject | Heart Ventricles/physiopathology | en |
| dc.subject | Humans | en |
| dc.subject | Myocardial Contraction/*physiology | en |
| dc.subject | Ventricular Function, Left/physiology | en |
| dc.title | The effects of ventricular asynchrony on myocardial perfusion | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.primary | 10.1016/j.ijcard.2006.03.091 | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/17056140 | - |
| heal.identifier.secondary | http://ac.els-cdn.com/S0167527306009880/1-s2.0-S0167527306009880-main.pdf?_tid=0327e0a8425e45d1b44b916801bb3211&acdnat=1333699575_af9f5636a3aa50dd787d27c620bb7553 | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 2007 | - |
| heal.abstract | Asynchronous depolarization and contraction sequence, secondary to intraventricular conduction defects or to permanent right ventricular apical pacing, is associated with adverse effects that may be clinically evident in the failing heart. Experimental and clinical studies have suggested that asynchronous ventricular contraction deteriorates left ventricular performance and induces unfavourable left ventricular remodelling. Although such contraction does not appear to affect resting coronary artery blood flow, it increases endomyocardial pressure during diastole and decreases regional myocardial perfusion in the interventricular septum. The magnitude of these effects may correlate with the duration of the asynchrony. Despite these detrimental effects, there is no evidence that ventricular asynchrony reduces collateral myocardial blood flow, myocardial oxygen consumption or cardiac efficiency, neither in patients with normal coronary arteries, nor in patients with coronary artery disease. Furthermore, in patients with acute ischaemic syndromes, ventricular asynchrony exerts a neutral effect on the ischaemic myocardium. Cardiac resynchronization therapy improves left ventricular systolic and diastolic function without an increase in myocardial oxygen consumption or energy cost. This therapy may decrease the inhomogeneity in regional oxidative metabolism, myocardial perfusion and cardiac efficiency. Further experimental and clinical studies are needed on this area. | en |
| heal.journalName | Int J Cardiol | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Kyriakides-2007-The effects of ventr.pdf | 672.06 kB | Adobe PDF | View/Open Request a copy |
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