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https://olympias.lib.uoi.gr/jspui/handle/123456789/24418Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Fotopoulos, A. D. | en |
| dc.contributor.author | Alexiou, G. A. | en |
| dc.contributor.author | Goussia, A. | en |
| dc.contributor.author | Papadopoulos, A. | en |
| dc.contributor.author | Kyritsis, A. P. | en |
| dc.contributor.author | Polyzoidis, K. S. | en |
| dc.contributor.author | Voulgaris, S. | en |
| dc.contributor.author | Tsiouris, S. | en |
| dc.date.accessioned | 2015-11-24T19:40:54Z | - |
| dc.date.available | 2015-11-24T19:40:54Z | - |
| dc.identifier.issn | 0167-594X | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/24418 | - |
| dc.rights | Default Licence | - |
| dc.subject | Aged | en |
| dc.subject | Brain/metabolism/*radionuclide imaging | en |
| dc.subject | Cell Proliferation | en |
| dc.subject | Female | en |
| dc.subject | Humans | en |
| dc.subject | Ki-67 Antigen/metabolism | en |
| dc.subject | Magnetic Resonance Imaging | en |
| dc.subject | Male | en |
| dc.subject | Meningeal Neoplasms/pathology/*radionuclide imaging | en |
| dc.subject | Meningioma/pathology/*radionuclide imaging | en |
| dc.subject | Middle Aged | en |
| dc.subject | Retrospective Studies | en |
| dc.subject | Statistics as Topic | en |
| dc.subject | Technetium Tc 99m Sestamibi/*diagnostic use | en |
| dc.subject | *Tomography, Emission-Computed, Single-Photon | en |
| dc.title | (99m)Tc-Tetrofosmin brain SPECT in the assessment of meningiomas-correlation with histological grade and proliferation index | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.primary | 10.1007/s11060-008-9611-8 | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/18458817 | - |
| heal.identifier.secondary | http://www.springerlink.com/content/l682w40l16tv7g63/fulltext.pdf | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 2008 | - |
| heal.abstract | Meningiomas account for about 30% of all intracranial tumors. Evaluation of their proliferation rate is useful for assessing their biological behavior. We evaluated prospectively whether (99m)Tc-Tetrofosmin ((99m)Tc-TF) uptake in meningiomas correlates with cellular proliferative activity and with tumor grade. We prospectively studied 18 meningioma cases. Brain single-photon emission computed tomography (SPECT) by (99m)Tc-TF was performed within a week prior to surgical excision. In the excised tumor specimens we assessed Ki-67 antigen expression. 14 of 18 patients had benign meningiomas, while the remaining four had anaplastic meningiomas. A significant correlation was found between both (99m)Tc-TF uptake and tumor grade (r = 0.722, P = 0.001) and between (99m)Tc-TF uptake and Ki-67 expression (r = 0.930, P < 0.001). There was a significant correlation between the intensity of tracer uptake and tumor recurrence at 1 year postoperative (r = 0.574, P = 0.02). This pilot study implies that (99m)Tc-TF brain SPECT could prove useful in differentiating benign from anaplastic meningiomas and is a potential indicator of their proliferative activity. | en |
| heal.journalName | J Neurooncol | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Fotopoulos-2008-(99m)Tc-Tetrofosmin.pdf | 260.59 kB | Adobe PDF | View/Open Request a copy |
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