Please use this identifier to cite or link to this item:
https://olympias.lib.uoi.gr/jspui/handle/123456789/24272Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Emfietzoglou, D. | en |
| dc.contributor.author | Moscovitch, M. | en |
| dc.date.accessioned | 2015-11-24T19:39:48Z | - |
| dc.date.available | 2015-11-24T19:39:48Z | - |
| dc.identifier.issn | 0031-9155 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/24272 | - |
| dc.rights | Default Licence | - |
| dc.subject | Benzopyrans | en |
| dc.subject | Color | en |
| dc.subject | Computing Methodologies | en |
| dc.subject | Gases | en |
| dc.subject | Kinetics | en |
| dc.subject | *Phantoms, Imaging | en |
| dc.subject | Photochemistry | en |
| dc.subject | Polymethyl Methacrylate | en |
| dc.subject | Probability | en |
| dc.subject | Radiation Dosage | en |
| dc.subject | Radiotherapy Dosage | en |
| dc.subject | *Radiotherapy Planning, Computer-Assisted | en |
| dc.subject | Sensitivity and Specificity | en |
| dc.subject | Time Factors | en |
| dc.title | A potential application to the study of microscopic energy deposition in a solid by means of heavy charged-particle induced photochromic alterations in a tissue-equivalent matrix | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/10071884 | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 1999 | - |
| heal.abstract | A theoretical study was carried out to investigate the feasibility of using the radiation-induced colour decay of photochromic molecules embedded in a polymer matrix as a probe for studying the microscopic energy deposition of heavy charged particles (HCPs) in a tissue-equivalent solid. The theoretical treatment makes use of the radial dose distribution function as derived from gas-phase physics, together with the effects of the increase in temperature and of matrix degradation on the colour-decay kinetics of the photochromic molecules, according to empirical models derived for the solid state. Bearing in mind the non-stochastic nature of the model, the use of gas-phase physics at the level of radiation interaction, and the fact that some empirical quantities used have been established macroscopically, all factors which signify that extra caution is required in the interpretation of the results, it is shown that when the optimum information retrieval time (after track formation) is considered the technique may be able to resolve differences in the energy deposition pattern by different HCPs in the nanometre range (1-10 nm; material's mass density 1.2 g cm(-3)) from the track axis. Most importantly, though, the present study aims to erect a theoretical framework for the possible application of the technique and to highlight those aspects which are likely to be critical to its practical usage, such as particle type and energy range, and spatial scale and magnitude of the expected effect together with its dependence on time, the physical characteristics of the matrix, and the kinetic behaviour of the type of photochromic molecule studied. Furthermore, it establishes a rationale for interpreting the experimentally observed (if available) colour changes in the HCP track in terms of the microscopic distribution of energy deposition in it. | en |
| heal.journalName | Phys Med Biol | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Emfietzoglou-1999-a potential application.pdf | 423.6 kB | Adobe PDF | View/Open Request a copy |
This item is licensed under a Creative Commons License
