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  5. Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ
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Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/24139
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dc.contributor.authorMilionis, H. J.en
dc.contributor.authorBourantas, C. L.en
dc.contributor.authorSiamopoulos, K. C.en
dc.contributor.authorElisaf, M. S.en
dc.date.accessioned2015-11-24T19:38:21Z-
dc.date.available2015-11-24T19:38:21Z-
dc.identifier.issn0361-8609-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/24139-
dc.rightsDefault Licence-
dc.subjectAcid-Base Imbalance/*etiologyen
dc.subjectAcidosis/etiologyen
dc.subjectAdolescenten
dc.subjectAdulten
dc.subjectAgeden
dc.subjectAged, 80 and overen
dc.subjectAlkalosis/etiologyen
dc.subjectAnoxia/etiologyen
dc.subjectElectrolytes/*blooden
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectHydrogen-Ion Concentrationen
dc.subjectHypocalcemia/etiologyen
dc.subjectHypokalemia/etiologyen
dc.subjectHyponatremia/etiologyen
dc.subjectHypophosphatemia/etiologyen
dc.subjectLeukemia, Myeloid, Acute/*complicationsen
dc.subjectMagnesium Deficiency/etiologyen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectPrecursor Cell Lymphoblastic Leukemia-Lymphoma/*complicationsen
dc.titleAcid-base and electrolyte abnormalities in patients with acute leukemiaen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/10589074-
heal.identifier.secondaryhttp://onlinelibrary.wiley.com/store/10.1002/(SICI)1096-8652(199912)62:4<201::AID-AJH1>3.0.CO;2-1/asset/1_ftp.pdf?v=1&t=h0m7ov10&s=88be6c9a780032437a79bf6559171441b896b046-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate1999-
heal.abstractDisturbances of acid-base balance and electrolyte abnormalities are commonly seen in patients with acute leukemia. Our study aimed at illuminating the probable pathogenetic mechanisms responsible for these disturbances in patients with acute leukemia admitted to our hospital. We studied 66 patients (24 men and 44 women) aged between 17 and 87 years old on their admission and prior to any therapeutic intervention. Patients with diabetes mellitus, acute or chronic renal failure, hepatic failure, patients receiving drugs that influence acid-base status and electrolyte parameters during the last month, such as corticosteroids, cisplatin, diuretics, antacids, aminoglycosides, amphotericin, penicillin, and K(+), PO(4)(3-), or Mg(2+) supplements were excluded. Forty-one patients had at least one acid-base or electrolyte disturbance. There were no significant differences in the incidence of acid-base balance and electrolyte abnormalities between patients with acute myeloid leukemia (AML) and patients with acute lymphoblastic leukemia (ALL). The most frequent electrolyte abnormality was hypokalemia, observed in 41 patients (63%), namely in 34 patients with AML, and 7 with ALL; the main underlying pathophysiologic mechanism was inappropriate kaliuresis. Furthermore, hypokalemic patients more frequently experienced concurrent electrolyte disturbances (i.e., hyponatremia, hypocalcemia, hypophosphatemia, and hypomagnesemia), as well as various acid-base abnormalities compared to normokalemic patients. Hypokalemia in patients with acute leukemia may serve as an indicator of multiple concurrent, interrelated electrolyte disturbances, especially in patients with AML.en
heal.journalNameAm J Hematolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
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