Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/24000
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dc.contributor.authorKalambokis, G.en
dc.contributor.authorKonitsiotis, S.en
dc.contributor.authorPappas, D.en
dc.contributor.authorTsianos, E. V.en
dc.date.accessioned2015-11-24T19:37:11Z-
dc.date.available2015-11-24T19:37:11Z-
dc.identifier.issn0391-4097-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/24000-
dc.rightsDefault Licence-
dc.subjectAddison Disease/diagnosis/*drug therapyen
dc.subjectAkinetic Mutism/*chemically induceden
dc.subjectBipolar Disorder/*chemically induceden
dc.subjectElectroencephalographyen
dc.subjectHormone Replacement Therapy/adverse effectsen
dc.subjectHumansen
dc.subjectHydrocortisone/administration & dosage/*adverse effectsen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.titleAkinetic mutism followed by a manic reaction on introduction of steroid replacement for Addison's diseaseen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/16682841-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2006-
heal.abstractNeuropsychiatric changes during exogenous corticosteroid administration are well-recognized. However, reports of neuropsychiatric reactions to corticosteroid replacement for Addison's disease are distinctively rare. We report on a patient with primary adrenocortical insufficiency, initially presenting with depressive symptoms, who developed akinetic mutism followed by acute manic illness shortly after the initiation of steroid replacement. Both disorders occurred with physiological doses of hydrocortisone and resolved spontaneously. The pathogenesis of the above neuropsychiatric reactions is discussed in the context of glucocorticoid receptor-related brain effects of glucocorticoids. In addition, this report points to the need for accurate psychiatric assessment of patients with Addison's disease upon introduction of replacement therapy.en
heal.journalNameJournal of Endocrinological Investigationen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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