Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/23967
Full metadata record
DC FieldValueLanguage
dc.contributor.authorFilippatos, T. D.en
dc.contributor.authorMilionis, H. J.en
dc.contributor.authorElisaf, M. S.en
dc.date.accessioned2015-11-24T19:36:57Z-
dc.date.available2015-11-24T19:36:57Z-
dc.identifier.issn0902-4441-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23967-
dc.rightsDefault Licence-
dc.subject*Acid-Base Imbalance/etiology/metabolismen
dc.subjectAntineoplastic Agents/adverse effects/metabolism/therapeutic useen
dc.subjectHeart Diseases/chemically induceden
dc.subjectHumansen
dc.subject*Leukemia/complications/drug therapy/metabolismen
dc.subjectMedlineen
dc.subject*Water-Electrolyte Imbalance/etiology/metabolismen
dc.titleAlterations in electrolyte equilibrium in patients with acute leukemiaen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1111/j.1600-0609.2005.00547.x-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/16313256-
heal.identifier.secondaryhttp://onlinelibrary.wiley.com/store/10.1111/j.1600-0609.2005.00547.x/asset/j.1600-0609.2005.00547.x.pdf?v=1&t=h0m64jn6&s=658d21e2a1cd26afc6e4951c0131bf2a0f254d52-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2005-
heal.abstractBACKGROUND AND AIM: A wide array of disturbances in electrolyte equilibrium is commonly seen in patients with acute leukemia (AL). These abnormalities present a potential hazard in these patients, as that of enhancing the cardiotoxic effects of certain chemotherapeutic regimens. The literature dealing with AL-related electrolyte abnormalities and their interactions in leukemic patients was reviewed. DATA SYNTHESIS: Sources included MEDLINE and EMBASE. The search strategy was based on the combination of 'acute leukemia', 'electrolyte abnormalities', 'acid-base disorders', 'potassium', 'sodium', 'magnesium', 'calcium', and 'phosphorus'. References of retrieved articles were also screened. A decrease in serum potassium, mainly owing to lysozyme-induced tubular damage, appears to be one of the most frequent and potentially hazardous abnormalities. Other clinically significant metabolic perturbations include hyponatremia and hypercalcemia. CONCLUSION: A broad spectrum of electrolyte abnormalities is encountered in the clinical setting of AL, which are related to the disease process per se and/or to the therapeutic interventions. Clinicians should be vigilant for early detection and appropriate management of these disorders before the initiation of chemotherapy regimens as well as during treatment.en
heal.journalNameEur J Haematolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

Files in This Item:
File Description SizeFormat 
Filippatos-2005-Alterations in elect.pdf138.44 kBAdobe PDFView/Open    Request a copy


This item is licensed under a Creative Commons License Creative Commons