Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/23933
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dc.contributor.authorLolis, D.en
dc.contributor.authorGeorgiou, I.en
dc.contributor.authorLoizou, P.en
dc.contributor.authorMakrydimas, G.en
dc.contributor.authorBairaktari, E.en
dc.contributor.authorTsolas, O.en
dc.date.accessioned2015-11-24T19:36:45Z-
dc.date.available2015-11-24T19:36:45Z-
dc.identifier.issn0378-7346-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23933-
dc.rightsDefault Licence-
dc.subjectAmniotic Fluid/*chemistry/metabolismen
dc.subjectAnencephaly/diagnosis/metabolismen
dc.subjectBiological Markers/analysisen
dc.subjectCongenital Abnormalities/*diagnosis/metabolismen
dc.subjectCross-Sectional Studiesen
dc.subjectFemaleen
dc.subjectFetal Diseases/*diagnosis/metabolismen
dc.subjectFetal Growth Retardation/diagnosis/metabolismen
dc.subjectHumansen
dc.subjectPrealbumin/*analysis/metabolismen
dc.subjectPregnancyen
dc.subjectPregnancy Trimester, Seconden
dc.subjectPregnancy Trimester, Thirden
dc.subjectReference Valuesen
dc.subjectSpinal Dysraphism/diagnosis/metabolismen
dc.titleAmniotic fluid prealbumin as a potential marker of fetal abnormalitiesen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/8586303-
heal.identifier.secondaryhttp://content.karger.com/ProdukteDB/produkte.asp?doi=10.1159/000292343-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate1995-
heal.abstractNormal amniotic fluid prealbumin (PAB) levels between 16 and 41 weeks of pregnancy are demonstrated in 175 samples from various gestational ages. PAB was measured quantitatively by immunonephelometry and qualitatively estimated by electrophoresis while total protein content was measured by colorimetry. The percent of PAB values in the total protein content is inversely correlated to the gestational age. Fetal abnormalities and abnormal conditions in pregnancy diagnosed in the second trimester and early third trimester (16-32 weeks) show significantly (p < 0.01) higher than expected PAB values (25.9 +/- 4.6 mg/l, range 19.5-35.6, n = 23) in comparison to normal fetuses and normal pregnancies of the same age (13.6 +/- 3.6 mg/l, range 4.3-19.8, n = 87). The remaining 65 samples of normal third trimester amniotic fluid were evaluated in comparison to the second trimester normal values, and inverse correlation in respect to advancing pregnancy was observed. PAB values were corrected for the total protein content and the resulting ratio had the lowest variation compared to PAB and total protein values. It is proposed that PAB, although not specific for a particular disorder, expressed as a ratio of the total protein content is a potential biochemical marker for certain fetal defects and complications of pregnancy.en
heal.journalNameGynecol Obstet Investen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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