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  4. Τμήμα Ιατρικής
  5. Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ
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Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/23831
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dc.contributor.authorTzarouchi, L. C.en
dc.contributor.authorKyritsis, A. P.en
dc.contributor.authorGiannopoulos, S.en
dc.contributor.authorAstrakas, L. G.en
dc.contributor.authorDiakou, M.en
dc.contributor.authorArgyropoulou, M. I.en
dc.date.accessioned2015-11-24T19:36:13Z-
dc.date.available2015-11-24T19:36:13Z-
dc.identifier.issn1748-880X-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23831-
dc.rightsDefault Licence-
dc.subjectCase-Control Studiesen
dc.subjectDiffusion Magnetic Resonance Imagingen
dc.subjectDisease Progressionen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectMiddle Ageden
dc.subjectMotor Neuron Disease/*pathology/physiopathologyen
dc.subjectMotor Neurons/physiologyen
dc.subjectNeural Conduction/physiologyen
dc.subjectPrognosisen
dc.subjectPyramidal Tracts/*pathology/physiopathologyen
dc.titleVoxel-based diffusion tensor imaging detects pyramidal tract degeneration in primary lateral sclerosisen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1259/bjr/14368804-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/21172968-
heal.identifier.secondaryhttp://bjr.birjournals.org/content/84/997/78.full.pdf-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2011-
heal.abstractOBJECTIVE: Primary lateral sclerosis (PLS) is a progressive degenerative disorder affecting upper motor neurons and requires a clinical diagnosis. Diffusion tensor imaging (DTI) is a quantitative method for assessing white matter fibre integrity. The purpose of the study was to evaluate the involvement of upper motor neurons by using DTI in PLS. METHODS: A patient with PLS was compared with eight age-matched controls. Differences in fractional anisotropy (FA) index were assessed using DTI on a voxel-by-voxel basis. RESULTS: Decreased FA was observed in the proximal part of the pyramidal tract bilaterally, which indicated degeneration of the pyramidal cells. CONCLUSION: Voxel-based DTI could be used as an objective marker for detecting upper motor neuron degeneration in PLS.en
heal.journalNameBr J Radiolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
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