Please use this identifier to cite or link to this item:
https://olympias.lib.uoi.gr/jspui/handle/123456789/23796Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Bakola, E. | en |
| dc.contributor.author | Skapinakis, P. | en |
| dc.contributor.author | Tzoufi, M. | en |
| dc.contributor.author | Damigos, D. | en |
| dc.contributor.author | Mavreas, V. | en |
| dc.date.accessioned | 2015-11-24T19:36:03Z | - |
| dc.date.available | 2015-11-24T19:36:03Z | - |
| dc.identifier.issn | 1090-3801 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/23796 | - |
| dc.rights | Default Licence | - |
| dc.subject | migraine | en |
| dc.subject | pediatric | en |
| dc.subject | prevention | en |
| dc.subject | anticonvulsants | en |
| dc.subject | efficacy | en |
| dc.subject | safety | en |
| dc.subject | placebo-controlled trial | en |
| dc.subject | quality-of-life | en |
| dc.subject | double-blind | en |
| dc.subject | follow-up | en |
| dc.subject | prophylactic treatment | en |
| dc.subject | childhood migraine | en |
| dc.subject | sodium valproate | en |
| dc.subject | children | en |
| dc.subject | topiramate | en |
| dc.subject | adolescents | en |
| dc.title | Anticonvulsant drugs for pediatric migraine prevention: An evidence-based review | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.primary | DOI 10.1016/j.ejpain.2008.11.004 | - |
| heal.identifier.secondary | <Go to ISI>://000272471800001 | - |
| heal.identifier.secondary | http://onlinelibrary.wiley.com/doi/10.1016/j.ejpain.2008.11.004/abstract | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 2009 | - |
| heal.abstract | Background: The use of anticonvulsant drugs for the prevention of migraine in children and adolescents has been supported in the past. Aims: To evaluate the available evidence for the efficacy and safety of anticonvulsants; drugs in the prevention of migraine attacks in children and adolescents. Methods: Studies were selected through a comprehensive literature search. We included all types of study designs (controlled and uncontrolled) due to the limited evidence. Monthly migraine frequency was used as the primary outcome measure in most of the studies. Studies were classified into levels of evidence according to their design. Results: Fourteen studies were included with a total of 939 patients. Topiramate (4 randomized controlled trials [RCT], two uncontrolled trials), sodium valproate/divalproex sodium (two RCTs, one uncontrolled trial, two retrospective chart reviews) levetiracetam and zonisamide (both only uncontrolled Studies) are the anticonvulsants that have been reported in the literature. The findings show that valproate is not different from placebo and topiramate may not be different but further randomized trials are needed. All drugs were well tolerated in this age group with no serious events reported. Conclusions: The use of anticonvulsants in the prevention of migraine in children and adolescents is not adequately supported by methodologically sound RCTs. More research is needed in the future to establish the efficacy and safety of specific agents. (C) 2008 European Federation of International Association for the Study of Pain Chapters. Published by Elsevier Ltd. All rights reserved. | en |
| heal.journalName | European Journal of Pain | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
Files in This Item:
There are no files associated with this item.
This item is licensed under a Creative Commons License
