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https://olympias.lib.uoi.gr/jspui/handle/123456789/23749Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Vlachos, K. | en |
| dc.contributor.author | Siafakas, N. | en |
| dc.contributor.author | Karameris, A. | en |
| dc.contributor.author | Athanasas, G. | en |
| dc.contributor.author | Theodoropoulos, G. | en |
| dc.contributor.author | Peros, G. | en |
| dc.contributor.author | Papadopoulos, J. | en |
| dc.contributor.author | Hakim, N. | en |
| dc.date.accessioned | 2015-11-24T19:35:48Z | - |
| dc.date.available | 2015-11-24T19:35:48Z | - |
| dc.identifier.issn | 0020-8868 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/23749 | - |
| dc.rights | Default Licence | - |
| dc.subject | Adenocarcinoma/*metabolism | en |
| dc.subject | Age Factors | en |
| dc.subject | Analysis of Variance | en |
| dc.subject | Antigens, CD95/*metabolism | en |
| dc.subject | Apoptosis | en |
| dc.subject | Cardia/metabolism/*pathology | en |
| dc.subject | Chi-Square Distribution | en |
| dc.subject | Cyclin-Dependent Kinase Inhibitor p21/*metabolism | en |
| dc.subject | Esophagogastric Junction/*pathology | en |
| dc.subject | Female | en |
| dc.subject | Humans | en |
| dc.subject | Immunoenzyme Techniques | en |
| dc.subject | Male | en |
| dc.subject | Middle Aged | en |
| dc.subject | Proto-Oncogene Proteins c-bcl-2/metabolism | en |
| dc.subject | Tumor Markers, Biological/metabolism | en |
| dc.subject | Tumor Suppressor Protein p53/*metabolism | en |
| dc.subject | bcl-X Protein/*metabolism | en |
| dc.title | Apoptosis and adenocarcinoma of the cardia: expression of p53, Bcl-2, Bcl-XL, WAF1, and fas proteins and association with characteristics of the tumors | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/18828269 | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 2008 | - |
| heal.abstract | Our knowledge regarding the biology of the gastroesophageal junction adenocarcinomas is still incomplete. Paraffin-embedded sections from 31 surgically resected primary cardia adenocarcinomas were examined by immunohistochemistry. Statistical analysis showed that Bcl-2 expression was significantly correlated with the age of the patients (P = 0.043), whereas Bcl-X(L) expression was inversely correlated with Bcl-2 expression (P = 0.021). An inverse correlation of high statistical significance was also found between p53 and Bcl-2 expression (P = 0.000). Fas expression was highly correlated with tumor stage (P = 0.006), degree of differentiation (P = 0.044), and the stage of the disease (P = 0.029). A significant correlation was also observed between the expression levels of WAF1 and Fas (P = 0.037), Fas and Bcl-X(L) (P = 0.018), and WAF1 and p53 (P = 0.018). These proteins may contribute to the estimation of the properties of adenocarcinomas of the gastroesophageal junction, facilitating prognosis of cancer patients treated by multimode therapy. | en |
| heal.journalName | Int Surg | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
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