Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/23423
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dc.contributor.authorAnasti, J. N.en
dc.contributor.authorKalantaridou, S. N.en
dc.contributor.authorKimzey, L. M.en
dc.contributor.authorDefensor, R. A.en
dc.contributor.authorNelson, L. M.en
dc.date.accessioned2015-11-24T19:32:33Z-
dc.date.available2015-11-24T19:32:33Z-
dc.identifier.issn0029-7844-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23423-
dc.rightsDefault Licence-
dc.subjectAbsorptiometry, Photonen
dc.subjectAdulten
dc.subjectBody Mass Indexen
dc.subjectBone Density/*physiologyen
dc.subjectBone Resorption/*physiopathology/radionuclide imagingen
dc.subjectFemaleen
dc.subjectFemur Neck/*physiology/radionuclide imagingen
dc.subjectHumansen
dc.subjectKaryotypingen
dc.subjectPrimary Ovarian Insufficiency/*complications/physiopathology/radionuclide imagingen
dc.subjectProspective Studiesen
dc.subjectSpine/*physiology/radionuclide imagingen
dc.titleBone loss in young women with karyotypically normal spontaneous premature ovarian failureen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/9464713-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate1998-
heal.abstractOBJECTIVE: To evaluate the effects of karotypically normal spontaneous premature ovarian failure on femoral neck bone mineral density. METHODS: Eighty-nine women with karyotypically normal spontaneous premature ovarian failure who desired fertility were evaluated at a tertiary care academic center and underwent hip and spinal bone density measurements by conventional dual-photon absorptiometry. Seventy-seven of the women (87%) had sought medical advice previously and had taken a variety of estrogen and progestin replacement regimens at least intermittently. The median (range) age was 32 (20-39) years, and the median (range) time since diagnosis was 1.5 (0.5-11) years. Findings were compared with a reference group of 218 regularly menstruating women of similar age. RESULTS: Sixty of the 89 women with premature ovarian failure (67%, 95% confidence interval 57, 77) had a femoral neck bone mineral density more than 1 standard deviation (SD) below the mean of the reference group (P < .001, chi2 with Yates correction). Even in women in whom the bone mineral density measurement was made within just 1.5 years of the diagnosis, nearly one-half (47%) had a femoral neck bone mineral density more than 1 SD below the mean of the reference group (P < .01). CONCLUSION: Two-thirds of young women with karyotypically normal spontaneous premature ovarian failure have a femoral neck bone mineral density more than 1 SD below the mean of a reference group. These young women need early education regarding strategies to maintain their bone mass and ongoing medical evaluation to maintain compliance with these strategies.en
heal.journalNameObstet Gynecolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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