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dc.contributor.authorPavlidis, N.en
dc.contributor.authorFizazi, K.en
dc.date.accessioned2015-11-24T19:31:48Z-
dc.date.available2015-11-24T19:31:48Z-
dc.identifier.issn1040-8428-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23327-
dc.rightsDefault Licence-
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectImmunophenotypingen
dc.subjectMaleen
dc.subjectNeoplasm Metastasis/diagnosis/*pathology/therapyen
dc.subjectPrognosisen
dc.titleCancer of unknown primary (CUP)en
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1016/j.critrevonc.2004.10.002-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/15890271-
heal.identifier.secondaryhttp://ac.els-cdn.com/S1040842804001738/1-s2.0-S1040842804001738-main.pdf?_tid=68863f884262096fe19abab97661fa0e&acdnat=1333612681_256ce49d8da10990ba656f6053a737b1-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2005-
heal.abstractCarcinoma of unknown primary (CUP) is one of the 10 most frequent cancers worldwide. It constitutes 3-5% of all human malignancies. Patients with CUP present with metastases without an established primary site. CUP manifests as an heterogenous group of mainly epithelial cancers recognised by distinct clinicopathological entities. The diagnostic work-up includes extensive histopathology investigations and modern imaging technology. Nevertheless, the primary tumour remains undetected most of the time. Certain clinicopathological CUP entities are considered as favourable subsets responding to systemic platinum-based chemotherapy or managed by locoregional treatment. These subsets are: the poorly differentiated carcinomas involving the mediastinal-retroperitoneal nodes, peritoneal papillary serous adenocarcinomatosis in females, poorly differentiated neuroendocrine carcinomas, isolated axillary node adenocarcinomas in females or cervical nodal involvement by a squamous cell carcinoma. Patients who belong to the non-favourable subsets have a worse prognosis.en
heal.journalNameCrit Rev Oncol Hematolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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