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dc.contributor.authorFotsis, T.en
dc.contributor.authorHeikkinen, R.en
dc.contributor.authorAdlercreutz, H.en
dc.contributor.authorAxelson, M.en
dc.contributor.authorSetchell, K. D.en
dc.date.accessioned2015-11-24T19:31:40Z-
dc.date.available2015-11-24T19:31:40Z-
dc.identifier.issn0009-8981-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23305-
dc.rightsDefault Licence-
dc.subject4-Butyrolactone/analogs & derivatives/urineen
dc.subjectAdulten
dc.subjectButylene Glycols/urineen
dc.subjectChromatography, Gas/*methodsen
dc.subjectChromatography, Ion Exchangeen
dc.subjectFemaleen
dc.subjectGas Chromatography-Mass Spectrometryen
dc.subjectGlucuronates/urineen
dc.subjectHumansen
dc.subjectLignansen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectPlant Extracts/*urineen
dc.titleCapillary gas chromatographic method for the analysis of lignans in human urineen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/6286168-
heal.identifier.secondaryhttp://ac.els-cdn.com/0009898182902455/1-s2.0-0009898182902455-main.pdf?_tid=ac7a94436721f69baec51c0ad32fdd9b&acdnat=1332751328_27f5d674ca9b024bd38f19efb870fa07-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate1982-
heal.abstractWe describe a capillary column gas chromatographic (GC) method for the analysis of lignans in urine. Lignans are excreted as mono-glucuronides which are first extracted on a small reversed-phase cartridge of octadecylsilane bonded silica (Sep-Pak C18) and thereafter isolated by anion exchange chromatography on DEAE-Sephadex A-25, prepared in the acetate form. Lignan mono-glucuronides are enzymatically hydrolysed and re-extracted on a Sep-Pak C18 cartridge. Quantification is carried out by capillary column GC of the trimethylsilyl ether derivatives. The specificity of the method was checked by GC/MS and the intra-assay coefficient of variation (CV) for the two lignans, enterolactone (trans-2,3-bis(3-hydroxybenzyl)butyrolactone) and enterodiol (2.3-bis(3-hydroxybenzyl)butane-1,4-diol) varied between 5 and 8%. Some values for the excretion of these lignans by normal men and women are presented.en
heal.journalNameClin Chim Actaen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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