Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/23239
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dc.contributor.authorTasoulis, D. K.en
dc.contributor.authorSpyridonos, P.en
dc.contributor.authorPavlidis, N. G.en
dc.contributor.authorPlagianakos, V. P.en
dc.contributor.authorRavazoula, P.en
dc.contributor.authorNikiforidis, G.en
dc.contributor.authorVrahatis, M. N.en
dc.date.accessioned2015-11-24T19:31:17Z-
dc.date.available2015-11-24T19:31:17Z-
dc.identifier.issn0933-3657-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23239-
dc.rightsDefault Licence-
dc.subjectAlgorithmsen
dc.subjectCell Nucleus/*pathologyen
dc.subjectFuzzy Logicen
dc.subjectHumansen
dc.subject*Models, Biologicalen
dc.subjectNeoplasm Recurrence, Local/*diagnosis/pathology/therapyen
dc.subjectNeoplasm Stagingen
dc.subjectPrognosisen
dc.subjectUrinary Bladder Neoplasms/classification/*diagnosis/*pathology/therapyen
dc.titleCell-nuclear data reduction and prognostic model selection in bladder tumor recurrenceen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1016/j.artmed.2006.07.008-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/17008071-
heal.identifier.secondaryhttp://ac.els-cdn.com/S0933365706001102/1-s2.0-S0933365706001102-main.pdf?_tid=f5f2553eecc4d25e2cd02cc843f46af1&acdnat=1333614085_d41b9367541f7348f16eee6d2d0bb0ac-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2006-
heal.abstractOBJECTIVE: The paper aims at improving the prediction of superficial bladder recurrence. To this end, feedforward neural networks (FNNs) and a feature selection method based on unsupervised clustering, were employed. MATERIAL AND METHODS: A retrospective prognostic study of 127 patients diagnosed with superficial urinary bladder cancer was performed. Images from biopsies were digitized and cell nuclei features were extracted. To design FNN classifiers, different training methods and architectures were investigated. The unsupervised k-windows (UKW) and the fuzzy c-means clustering algorithms were applied on the feature set to identify the most informative feature subsets. RESULTS: UKW managed to reduce the dimensionality of the feature space significantly, and yielded prediction rates 87.95% and 91.41%, for non-recurrent and recurrent cases, respectively. The prediction rates achieved with the reduced feature set were marginally lower compared to the ones attained with the complete feature set. The training algorithm that exhibited the best performance in all cases was the adaptive on-line backpropagation algorithm. CONCLUSIONS: FNNs can contribute to the accurate prognosis of bladder cancer recurrence. The proposed feature selection method can remove redundant information without a significant loss in predictive accuracy, and thereby render the prognostic model less complex, more robust, and hence suitable for clinical use.en
heal.journalNameArtif Intell Meden
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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