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  4. Τμήμα Ιατρικής
  5. Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ
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Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/23228
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dc.contributor.authorHermans, M. P.en
dc.contributor.authorCastro Cabezas, M.en
dc.contributor.authorStrandberg, T.en
dc.contributor.authorFerrieres, J.en
dc.contributor.authorFeely, J.en
dc.contributor.authorElisaf, M. S.en
dc.contributor.authorMichel, G.en
dc.contributor.authorSansoy, V.en
dc.date.accessioned2015-11-24T19:31:13Z-
dc.date.available2015-11-24T19:31:13Z-
dc.identifier.issn1473-4877-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23228-
dc.rightsDefault Licence-
dc.subjectAdolescenten
dc.subjectAdulten
dc.subjectAgeden
dc.subjectAged, 80 and overen
dc.subjectAlgorithmsen
dc.subjectCross-Sectional Studiesen
dc.subjectEuropeen
dc.subjectFemaleen
dc.subjectGuideline Adherenceen
dc.subjectHealth Planning Guidelinesen
dc.subjectHumansen
dc.subjectHypercholesterolemia/blood/*therapyen
dc.subjectLipids/blooden
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectTreatment Failureen
dc.subjectYoung Adulten
dc.titleCentralized Pan-European survey on the under-treatment of hypercholesterolaemia (CEPHEUS): overall findings from eight countriesen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1185/03007990903500565-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/20001658-
heal.identifier.secondaryhttp://informahealthcare.com/doi/abs/10.1185/03007990903500565-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2010-
heal.abstractBACKGROUND: Surveys evaluating plasma lipid goal attainment in patients with coronary heart disease have shown that hypercholesterolaemia is inadequately treated. Limited data account for the reasons behind this. The aim of the CEntralized Pan-European survey on tHE Under-treatment of hypercholeSterolaemia (CEPHEUS) survey was to evaluate the current use and efficacy of lipid-lowering drugs (LLD), and to identify possible patient/physician characteristics associated with failure to achieve low-density lipoprotein cholesterol (LDL-C) targets recommended by the 2003 European guidelines (Third Joint Task Force). METHODS: CEPHEUS was a European, multi-centre, cross-sectional survey conducted in eight countries and involved patients on LLD for >3 months (stable medication >6 weeks). One visit was scheduled for data collection, including fasting lipids. In all but one country, physicians and patients filled in a questionnaire about aspects of hypercholesterolaemia and treatment. RESULTS: Of the 15 199 patients recruited, 14 478 were included in the final analyses. The mean age was 63.2 years, and 45% of patients were female. Overall, 55.3% of the patients achieved their LDL-C target. In multivariate analyses, the factors identified as positive predictors for achieving LDL-C goals included normal body mass index, not smoking, not having metabolic syndrome, being on statin therapy and good treatment adherence. LIMITATIONS: The population was a selected group of subjects treated with LLD, and the results cannot be extrapolated to the general population. Patient consent was obtained, which may have selected more motivated patients and induced a positive bias. The physician and patient questionnaires were not validated, but were only used for exploratory purposes. CONCLUSION: Only 55.3% of patients using LLD achieved the LDL-C target recommended in the 2003 European guidelines.en
heal.journalNameCurrent Medical Research and Opinionen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
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