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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Maniotis, C. | en |
| dc.contributor.author | Tsalikakis, D. G. | en |
| dc.contributor.author | Tzallas, A. T. | en |
| dc.contributor.author | Varnavas, V. | en |
| dc.contributor.author | Kontaras, K. | en |
| dc.contributor.author | Glava, C. | en |
| dc.contributor.author | Baltogiannis, G. G. | en |
| dc.contributor.author | Papalois, A. | en |
| dc.contributor.author | Kolettis, T. M. | en |
| dc.contributor.author | Kyriakides, Z. S. | en |
| dc.date.accessioned | 2015-11-24T19:30:33Z | - |
| dc.date.available | 2015-11-24T19:30:33Z | - |
| dc.identifier.issn | 1791-7549 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/23121 | - |
| dc.rights | Default Licence | - |
| dc.subject | Action Potentials | en |
| dc.subject | Animals | en |
| dc.subject | Electrocardiography | en |
| dc.subject | Heart Rate | en |
| dc.subject | Hindlimb/*blood supply | en |
| dc.subject | *Ischemic Preconditioning | en |
| dc.subject | Muscle, Skeletal/*blood supply | en |
| dc.subject | Myocardial Infarction/*complications/pathology | en |
| dc.subject | Myocardial Reperfusion Injury/*complications | en |
| dc.subject | Myocardium/pathology | en |
| dc.subject | Rats | en |
| dc.subject | Rats, Wistar | en |
| dc.subject | Tachycardia, Ventricular/etiology/*prevention & control | en |
| dc.title | Chronic skeletal muscle ischemia in rats decreases the inducibility of ventricular tachyarrhythmias after myocardial infarction | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/21753134 | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 2011 | - |
| heal.abstract | BACKGROUND: Chronic hind-limb ischemia confers cytoprotection after coronary occlusion, but it is unclear whether it ameliorates substrate formation for ventricular tachyarrhythmias (VTs). MATERIALS AND METHODS: Chronic hind-limb ischemia was generated by femoral artery excision in 50 rats, while 25 animals were sham-operated. Left coronary artery ligation was performed after 3 weeks and infarct size was measured 24 hours thereafter. The inducibility of VTs was assessed by programmed electrical stimulation (PES) 4 weeks post-ligation. A score was assigned, based on protocol stage and tachyarrhythmia duration. Monophasic action potentials (MAP) were recorded prior to and 4 weeks after ligation. RESULTS: The infarct size was smaller (p=0.000079) in the ischemic rats (25.7+/-2.1%) than in the controls (41.7+/-2.2%), accompanied by a lower (p=0.029) arrhythmia score (1.05+/-0.38 versus 2.70+/-0.68, respectively). The action potential duration (APD) was shorter (p<0.05) in the ischemic rats prior to ligation and remained stable after 4 weeks. CONCLUSION: Chronic hind limb ischemia limits infarct size and decreases inducible ventricular tachyarrhythmias. | en |
| heal.journalName | In Vivo | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
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