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dc.contributor.authorAssimakopoulos, D.en
dc.contributor.authorPatrikakos, G.en
dc.date.accessioned2015-11-24T19:30:27Z-
dc.date.available2015-11-24T19:30:27Z-
dc.identifier.issn0196-0709-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23098-
dc.rightsDefault Licence-
dc.subjectotolaryngologic manifestationsen
dc.subjectgastric-aciden
dc.subjectdiseaseen
dc.subjectesophagusen
dc.subjectcanceren
dc.subjectlaryngitisen
dc.subjectgastropharyngealen
dc.subjectcomplicationsen
dc.subjectsecondaryen
dc.subjectsmokingen
dc.titleThe role of gastroesophageal reflux in the pathogenesis of laryngeal carcinomaen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primaryDOI 10.1053/ajot.2002.128038-
heal.identifier.secondary<Go to ISI>://000179474200006-
heal.identifier.secondaryhttp://www.sciencedirect.com/science/article/pii/S0196070902000546-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2002-
heal.abstractGastroesophageal reflux (GER) has been strongly associated with carcinogenesis of the lower esophagus and development of several otolaryngologic disorders. Epidemiologic studies support concept that the malignant transformation of laryngeal mucosal surfaces is due to GER-initiated chronic laryngeal inflammation. However, large clinical studies with matched control groups and further experimental investigations are necessary to ascertain the relationship between reflux and laryngeal carcinoma. This review stresses that early diagnosis of GER disease, based on clinical suspicion, ambulatory 24-hour double-probe pH monitoring, and endoscopic examination, as well as effective treatment of reflux, are considered the keys for relief of symptomatology and preventing the chronic irritation of the laryngeal mucosa that may contribute to the development of laryngeal carcinoma. Copyright 2002, Elsevier Science (USA). All rights reserved.en
heal.journalNameAmerican Journal of Otolaryngologyen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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