Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/23019
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dc.contributor.authorMakrydimas, G.en
dc.contributor.authorVandecruys, H.en
dc.contributor.authorSotiriadis, A.en
dc.contributor.authorLakasing, L.en
dc.contributor.authorSpencer, K.en
dc.contributor.authorNicolaides, K. H.en
dc.date.accessioned2015-11-24T19:30:06Z-
dc.date.available2015-11-24T19:30:06Z-
dc.identifier.issn1015-3837-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23019-
dc.rightsDefault Licence-
dc.subjectAbortion, Missed/*metabolismen
dc.subjectAmniotic Fluid/*metabolismen
dc.subjectFemaleen
dc.subjectFetal Death/metabolismen
dc.subjectHumansen
dc.subjectLeptin/blood/*metabolismen
dc.subjectOxygen/metabolismen
dc.subjectPlacenta/metabolismen
dc.subjectPregnancyen
dc.subjectPregnancy Trimester, First/*metabolismen
dc.titleCoelomic fluid leptin concentration in normal first-trimester pregnancies and missed miscarriagesen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1159/000086821-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/16113562-
heal.identifier.secondaryhttp://content.karger.com/ProdukteDB/produkte.asp?doi=10.1159/000086821-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2005-
heal.abstractOBJECTIVE: Investigation of the possible role of leptin in early pregnancy failure. METHODS: Leptin concentration was measured in maternal serum, coelomic fluid and amniotic fluid from 15 singleton pregnancies with live fetuses and 7 missed miscarriages at 7-10 weeks of gestation. RESULTS: In the pregnancies with live fetuses, the median leptin concentration was significantly higher in coelomic fluid (median 33.1 ng/ml) than in maternal serum (median 8.1 ng/ml) or amniotic fluid (median 0.5 ng/ml). In the pregnancies with missed miscarriage, compared to those with live fetuses, the median leptin concentration in coelomic fluid was higher (median 45.3 ng/ml), but in maternal serum it was not significantly different (median 5.5 ng/ml). CONCLUSIONS: The high coelomic fluid leptin concentration suggests that embryonic death may be preceded by impaired oxygenation of the placenta that stimulates production of leptin.en
heal.journalNameFetal Diagn Theren
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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