Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/22966
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dc.contributor.authorTsouli, S. G.en
dc.contributor.authorLiberopoulos, E. N.en
dc.contributor.authorKiortsis, D. N.en
dc.contributor.authorMikhailidis, D. P.en
dc.contributor.authorElisaf, M. S.en
dc.date.accessioned2015-11-24T19:29:21Z-
dc.date.available2015-11-24T19:29:21Z-
dc.identifier.issn1074-2484-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/22966-
dc.rightsDefault Licence-
dc.subjectAngiotensin II Type 1 Receptor Blockers/administration & dosage/*therapeutic useen
dc.subjectAngiotensin-Converting Enzyme Inhibitors/administration & dosage/*therapeutic useen
dc.subjectCardiovascular Diseases/*drug therapyen
dc.subjectClinical Trials as Topicen
dc.subjectDrug Therapy, Combinationen
dc.subjectHumansen
dc.subjectHypertension/drug therapyen
dc.subjectRenal Insufficiency/prevention & controlen
dc.subjectRenin-Angiotensin System/drug effectsen
dc.subjectStroke/prevention & controlen
dc.titleCombined treatment with angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers: a review of the current evidenceen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/16703216-
heal.identifier.secondaryhttp://cpt.sagepub.com/content/11/1/1.full.pdf-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2006-
heal.abstractSeveral studies have shown that angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers are useful in the treatment of hypertension, cardiovascular disease, chronic heart failure, and some types of nephropathy. In this context, dual renin-angiotensin system blockade with both angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers may be more effective than treatment with each agent alone. Many clinical trials have demonstrated the beneficial effect of this combined treatment on proteinuria, hypertension, heart failure, and cardiovascular events. Moreover, these studies demonstrated that dual renin-angiotensin system blockade is generally safe and well tolerated. Long-term studies are under way to confirm these effects and also investigate the effectiveness of dual renin-angiotensin system blockade on cerebrovascular disease and prevention of type 2 diabetes mellitus. These studies are expected to define the optimal use of combination treatment in everyday clinical practice. This review considers the most important clinical trials that evaluated the effect of dual renin-angiotensin system blockade on blood pressure, heart failure, and renal function.en
heal.journalNameJ Cardiovasc Pharmacol Theren
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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