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dc.contributor.authorPentheroudakis, G.en
dc.contributor.authorWhite, J.en
dc.contributor.authorDavis, J.en
dc.contributor.authorBrown, I.en
dc.contributor.authorVasey, P.en
dc.date.accessioned2015-11-24T19:27:54Z-
dc.date.available2015-11-24T19:27:54Z-
dc.identifier.issn0090-8258-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/22851-
dc.rightsDefault Licence-
dc.subjectAdenocarcinoma/*drug therapy/pathology/surgeryen
dc.subjectAgeden
dc.subjectAntineoplastic Combined Chemotherapy Protocols/*therapeutic useen
dc.subjectChoriocarcinoma, Non-gestational/*drug therapy/pathology/surgeryen
dc.subjectCombined Modality Therapyen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectOvarian Neoplasms/*drug therapy/pathology/surgeryen
dc.subjectPeritoneal Neoplasms/*drug therapy/pathology/surgeryen
dc.titleConcurrent ovarian-type primary peritoneal adenocarcinoma and peritoneal choriocarcinoma. A case report and review of the literatureen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1016/j.ygyno.2003.10.049-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/14766269-
heal.identifier.secondaryhttp://ac.els-cdn.com/S0090825803007649/1-s2.0-S0090825803007649-main.pdf?_tid=0a3ce2605ed1bf5f0e8a08a8f0dd8697&acdnat=1333955113_9bd090627085562cf254017501956e8f-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2004-
heal.abstractBACKGROUND: Nongestational choriocarcinomas are aggressive tumours occurring either as a global event or as a focal change in solid tumours. The latter is responsible for coexistence of trophoblastic histology with other malignancies. CASE: A 65-year old female with stage IV primary peritoneal carcinoma, ovarian type, underwent surgical cytoreduction followed by two courses of paclitaxel/carboplatin chemotherapy. A choriocarcinomatous component was later identified in the resection specimens, as chemotherapy resulted in a differential response of the two malignant variants. Commencement of EMA/CO chemotherapy (etoposide, methotrexate, actinomycin D, cyclophosphamide, vincristine) resulted in symptom palliation and tumour regression, further consolidated with platinum-based EP/EMA (etoposide, cisplatin, methotrexate, actinomycin D). Two months later, relentless choriocarcinomatous disease progression followed, leading to the patient's death while the peritoneal adenocarcinomatous variant remained biochemically quiescent. CONCLUSION: Choriocarcinomas may coexist with typical ovarian-type peritoneal cancer, creating diagnostic and therapeutic dilemmas. Aggressive weekly chorio-type chemotherapy appears to be warranted despite the low likelihood of cure, as it provides significant symptom palliation.en
heal.journalNameGynecol Oncolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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