Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/22484
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dc.contributor.authorKalambokis, G. N.en
dc.contributor.authorPappas, K.en
dc.contributor.authorTsianos, E. V.en
dc.date.accessioned2015-11-24T19:24:29Z-
dc.date.available2015-11-24T19:24:29Z-
dc.identifier.issn1940-1574-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/22484-
dc.rightsDefault Licence-
dc.titleDifferential effects of terlipressin on pulmonary and systemic hemodynamics in patients with cirrhosis and pulmonary hypertension: an echo studyen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1177/0003319711411704-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/21733953-
heal.identifier.secondaryhttp://ang.sagepub.com/content/63/3/199.full.pdf-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2012-
heal.abstractTerlipressin has been associated with pulmonary arterial vasodilation in patients with pulmonary hypertension (PH). We investigated the effects of terlipressin on pulmonary vascular resistance (PVR) in patients with cirrhosis without and with PH. Pulmonary vascular resistance and cardiac output (CO) by Doppler ultrasound, mean arterial pressure (MAP), and systemic vascular resistance (SVR) were evaluated in patients with cirrhosis with PVR -120 dyne s cm (group 1, n = 20) and PVR >120 dyne s cm (group 2, n = 10) before and 30 minutes after terlipressin infusion (2 mg). After terlipressin, PVR increased significantly in group 1 (96.1 +/- 20.2 vs 85.1 +/- 18 dyne s cm; P = .004) but decreased significantly in group 2 (170.4 +/- 37.8 vs 157.8 +/- 28.1 dyne s cm; P= .04). Pulmonary vascular resistance changes in group 2 correlated significantly with baseline PVR (r = -0.632; P = .04). Terlipressin induced a significant increase in MAP and SVR and a significant decrease in CO in both groups. Terlipressin significantly reduces pulmonary pressures in patients with cirrhosis having PH together with systemic hemodynamic improvement.en
heal.journalNameAngiologyen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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