1. Repository of OAI
  2. ΑΠΟΘΕΤΗΡΙΟ "ΟΛΥΜΠΙΑΣ"
  3. Σχολή Επιστημών Υγείας
  4. Τμήμα Ιατρικής
  5. Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ
Ελληνικά   English  
Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/22353
Full metadata record
DC FieldValueLanguage
dc.contributor.authorKarfis, E. A.en
dc.contributor.authorPapadopoulos, G.en
dc.contributor.authorMatsagas, M.en
dc.contributor.authorPantazi, D.en
dc.contributor.authorLekka, M.en
dc.contributor.authorKitsiouli, I.en
dc.contributor.authorSiminelakis, S.en
dc.contributor.authorAnagnostopoulos, C.E.en
dc.contributor.authorDrossos, G.en
dc.date.accessioned2015-11-24T19:23:41Z-
dc.date.available2015-11-24T19:23:41Z-
dc.identifier.issn0021-9509-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/22353-
dc.rightsDefault Licence-
dc.subjectAgeden
dc.subject*Coronary Artery Bypass/adverse effectsen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectInflammation Mediators/*blooden
dc.subjectInterleukin-10/blooden
dc.subjectInterleukin-6/blooden
dc.subjectInterleukin-8/blooden
dc.subjectMaleen
dc.subject*Stroke Volumeen
dc.subjectSystemic Inflammatory Response Syndrome/etiology/physiopathologyen
dc.subjectTumor Necrosis Factor-alpha/blooden
dc.subjectVentricular Dysfunction, Left/*blood/physiopathologyen
dc.titleThe systemic inflammatory response in coronary artery bypass grafting: what is the role of the very low ejection fraction (EF < or = 30%)?en
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/19043394-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2008-
heal.abstractAIM: Patients with depressed left ventricular function are more susceptible to develop postoperative complications after cardiac surgery. The aim of the present study was to examine the effect of severe left ventricular dysfunction on the activation of systemic inflammatory reaction during and after coronary artery bypass grafting (CABG). METHODS: Clinical prospective study; 32 selected patients underwent CABG; 16 patients had depressed left ventricular function before the operation (low ejection fraction [EF] <30%)--Low EF group (study group). Sixteen patients had normal left ventricular function (normal EF, >50%)--Normal EF group (control group). The levels of inflammatory mediators TNF-alpha, IL-6, IL-8 and IL-10 were measured preoperatively, during and after cardiopulmonary bypass (CPB) and 24 hours postoperatively. RESULTS: Higher levels of almost all of inflammatory mediators were detected in patients with depressed left ventricular function compared with patients of normal EF group. IL-6 levels were found statistically significant higher in Low EF group before the induction of anesthesia (P=0.039) and after the administration of protamine (P=0.02). IL-8 levels were found statistically significant higher in Low EF group before the induction of anesthesia (P=0.05), 30 min after the start of CPB (P=0.02), after the administration of protamine (P=0.015) and 24 hours after the end of the operation (P=0.05). No statistically significant differences were demonstrated between the 2 groups of study relative to TNF-alpha and IL-10. CONCLUSION: A greater activation of systemic inflammatory reaction occurred in patients with depressed left ventricular function than in patients with normal cardiac function when they underwent CABG with extracorporeal circulation.en
heal.journalNameJ Cardiovasc Surg (Torino)en
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

Show simple item record
Files in This Item:
There are no files associated with this item.
Show simple item record  


This item is licensed under a Creative Commons License Creative Commons