Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/22305
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dc.contributor.authorTsimihodimos, V.en
dc.contributor.authorDounousi, E.en
dc.contributor.authorSiamopoulos, K. C.en
dc.date.accessioned2015-11-24T19:23:26Z-
dc.date.available2015-11-24T19:23:26Z-
dc.identifier.issn1421-9670-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/22305-
dc.rightsDefault Licence-
dc.subjectDyslipidemias/*complications/*pathology/therapyen
dc.subjectErythropoietin/metabolismen
dc.subjectHumansen
dc.subjectHypertriglyceridemia/metabolismen
dc.subjectKidney Failure, Chronic/*complications/*pathology/therapyen
dc.subjectKidney Transplantation/methodsen
dc.subjectLipid Metabolismen
dc.subjectLipids/chemistryen
dc.subjectModels, Biologicalen
dc.subjectNephrotic Syndrome/metabolismen
dc.subjectPeritoneal Dialysisen
dc.subjectRecombinant Proteinsen
dc.subjectRenal Dialysisen
dc.subjectTreatment Outcomeen
dc.titleDyslipidemia in chronic kidney disease: an approach to pathogenesis and treatmenten
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1159/000144024-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/18612199-
heal.identifier.secondaryhttp://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowPDF&ArtikelNr=000144024&Ausgabe=239023&ProduktNr=223979&filename=000144024.pdf-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2008-
heal.abstractBACKGROUND/AIMS: Cardiovascular disease (CVD) is a major cause of mortality in patients with mild to moderate chronic kidney disease (CKD) and end-stage renal disease (ESRD). Dyslipidemia has been established as a well-known traditional risk factor for CVD in the general population and it is well known that patients with CKD exhibit significant alterations in lipoprotein metabolism. In this review the pathogenesis and treatment of renal dyslipidemia are discussed. METHODS: Studies on lipid abnormalities in CKD stages 1-4, in nephrotic syndrome, and in hemodialysis and peritoneal dialysis patients are analyzed, as well as the lipid profile of kidney graft recipients. Also, the results of the effects of epoietin treatment and hypolipidemic drugs in CKD patients are reported. RESULTS: Disturbances in lipoprotein metabolism are evident even at the early stages of CKD and usually follow a downhill course that parallels the decline of renal function. However, several intrinsic or exogenous factors can influence the phenotypic expression of these alterations. According to the literature, current evidence suggests that unlike dialysis patients, mild to moderate CKD patients could be benefit from the use of statins. CONCLUSION: The use of statins is indicated in patients with mild to moderate CKD, while in subjects with ESRD lipid-lowering therapy should be individualized.en
heal.journalNameAm J Nephrolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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