Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorDerdemezis, C. S.en
dc.contributor.authorKiortsis, D. N.en
dc.contributor.authorTsimihodimos, V.en
dc.contributor.authorPetraki, M. P.en
dc.contributor.authorVezyraki, P.en
dc.contributor.authorElisaf, M. S.en
dc.contributor.authorTselepis, A. D.en
dc.rightsDefault Licence-
dc.titleEffect of Plant Polyphenols on Adipokine Secretion from Human SGBS Adipocytesen
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.abstractIntroduction. Adipose tissue contributes to atherosclerosis with mechanisms related to adipokine secretion. Polyphenols may exhibit antiatherogenic properties. The aim of the study was to investigate the effects of three polyphenols, namely, quercetin, epigallocatechin gallate (EGCG), and resveratrol on adipokine secretion from cultured human adipocytes. Methods. Human SGBS adipocytes were treated with quercetin, EGCG, and resveratrol for 24 and 48 hours. Visfatin, leptin, and adiponectin were measured in the supernatant. Results. Visfatin secretion was inhibited by quercetin 10 muM by 16% and 24% at 24 and 48 hours respectively. The corresponding changes for quercetin 25 muM were 47% and 48%. Resveratrol 25 muM reduced visfatin by 28% and 38% at 24 and 48 hours. EGCG did not have an effect on visfatin. None of tested polyphenols influenced leptin and adiponectin secretion. Conclusion. Quercetin and resveratrol significantly decreased visfatin secretion from SGBS adipocytes. This effect may contribute to their overall antiatherogenic properties.en
heal.journalNameBiochem Res Inten
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

Files in This Item:
File Description SizeFormat 
Derdemezis-2011-Effect of Plant Poly.pdf606.43 kBAdobe PDFView/Open

This item is licensed under a Creative Commons License Creative Commons