Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/22143
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dc.contributor.authorKatopodis, K. P.en
dc.contributor.authorAndrikos, E.en
dc.contributor.authorPappas, M.en
dc.contributor.authorSiamopoulos, K. C.en
dc.date.accessioned2015-11-24T19:22:05Z-
dc.date.available2015-11-24T19:22:05Z-
dc.identifier.issn0391-3988-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/22143-
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectAgeden
dc.subjectAluminum Hydroxide/*administration & dosageen
dc.subjectDrug Administration Scheduleen
dc.subject*Feeding Behavioren
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectKidney Failure, Chronic/blood/therapyen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectPhosphates/*blooden
dc.subject*Renal Dialysisen
dc.titleEffectiveness of aluminum hydroxide timing administration in relation to meals in controlling hyperphosphatemia in dialysis patientsen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/16211530-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2005-
heal.abstractPhosphate binder compounds contribute to the control of hyperphosphatemia in hemodialysis (HD) patients. However, the most effective schedule of administration of phosphate binders in relation to meals is not well documented. We examined the effectiveness of aluminum hydroxide intake as the sole phosphate binder in relation to meals. Eighty-five patients on regular HD (45 male, 40 female), age 21-72 years, with a duration of 6-216 months HD participated in the study. In all patients, phosphate binders were discontinued for a one month period. Thereafter, and according to the protocol, all patients were advised to take aluminum hydroxide [Al(OH)3 ] 30 min before, during and 30 min after meals for 3 periods of one month each, in a random order. One month washout period preceded the periods of Al(OH)3 ingestion. When Al(OH)3 was administered 30 min prior to the meals, serum phosphate decreased by 7.0% (0.59 mg/dL), while when administrated with or 30 min after meals, it decreased statistically significantly by 28.5% (2.08 mg/dL), and 16% (1.29 mg/dL) respectively. Our results suggest that the efficacy of Al(OH)3 to bind phosphate salts and thus to prevent the hyperphosphatemia in HD patients is higher when this drug is taken with meals.en
heal.journalNameInt J Artif Organsen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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