Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/22001
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dc.contributor.authorKolibianakis, E. M.en
dc.contributor.authorZikopoulos, K.en
dc.contributor.authorSmitz, J.en
dc.contributor.authorCamus, M.en
dc.contributor.authorTournaye, H.en
dc.contributor.authorVan Steirteghem, A. C.en
dc.contributor.authorDevroey, P.en
dc.date.accessioned2015-11-24T19:19:59Z-
dc.date.available2015-11-24T19:19:59Z-
dc.identifier.issn0268-1161-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/22001-
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectEmbryo Transferen
dc.subjectFemaleen
dc.subject*Fertilization in Vitroen
dc.subjectFollicle Stimulating Hormone/therapeutic useen
dc.subjectGonadotropin-Releasing Hormone/*antagonists & inhibitorsen
dc.subjectHumansen
dc.subject*Ovulation Inductionen
dc.subjectPregnancyen
dc.subject*Pregnancy Rateen
dc.subjectProgesterone/*blooden
dc.subjectProspective Studiesen
dc.subjectRecombinant Proteins/therapeutic useen
dc.titleElevated progesterone at initiation of stimulation is associated with a lower ongoing pregnancy rate after IVF using GnRH antagonistsen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1093/humrep/deh272-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/15155603-
heal.identifier.secondaryhttp://humrep.oxfordjournals.org/content/19/7/1525.full.pdf-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2004-
heal.abstractBACKGROUND: The objective of this prospective study was to assess the impact of elevated serum progesterone levels on day 2 of the cycle on pregnancy rates in patients treated by IVF using GnRH antagonists. METHODS: Ovarian stimulation was started on day 2 of the cycle if progesterone levels were normal (normal-P group, n = 390). In the presence of elevated progesterone, initiation of stimulation was postponed for 1 or 2 days (high-P group, n = 20) and was started if repeat progesterone levels returned to normal range (n = 16). Stimulation was performed with recombinant FSH (rFSH) and GnRH antagonist was always started on day 6 of stimulation. RESULTS: A significantly higher exposure to progesterone and a significantly lower exposure to estradiol was present in the high-P as compared with the normal-P group from day 1 to day 8 of stimulation. In addition, a significantly lower ongoing pregnancy rate both per started cycle (5.0% versus 31.8%; P = 0.01) and per embryo transfer (6.3% versus 36.9%; P = 0.01) was present in the high-P compared with the normal-P group, respectively. CONCLUSIONS: The presence of elevated serum progesterone on day 2 of the cycle is associated with a decreased chance of pregnancy in patients treated with rFSH and GnRH antagonists.en
heal.journalNameHum Reproden
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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