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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Voulgari, P. V. | en |
dc.date.accessioned | 2015-11-24T19:19:54Z | - |
dc.date.available | 2015-11-24T19:19:54Z | - |
dc.identifier.issn | 1744-7623 | - |
dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/21995 | - |
dc.rights | Default Licence | - |
dc.subject | Animals | en |
dc.subject | Antirheumatic Agents/*therapeutic use | en |
dc.subject | Arthritis, Rheumatoid/*drug therapy | en |
dc.subject | Drugs, Investigational/*therapeutic use | en |
dc.subject | Humans | en |
dc.title | Emerging drugs for rheumatoid arthritis | en |
heal.type | journalArticle | - |
heal.type.en | Journal article | en |
heal.type.el | Άρθρο Περιοδικού | el |
heal.identifier.primary | 10.1517/14728214.13.1.175 | - |
heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/18321156 | - |
heal.identifier.secondary | http://informahealthcare.com/doi/abs/10.1517/14728214.13.1.175 | - |
heal.language | en | - |
heal.access | campus | - |
heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
heal.publicationDate | 2008 | - |
heal.abstract | BACKGROUND: Rheumatoid arthritis (RA) is a chronic, inflammatory, systemic, autoimmune disease characterized by symmetric arthritis of diarthrodial joints leading to progressive erosion of cartilage and bone. The individual and social impacts of RA are of great importance. OBJECTIVE: To investigate the development of new therapies for RA treatment. METHODS: Various databases have been searched for new drugs in clinical trials (Phase I - III) and experimental future therapeutic agents for RA. RESULTS/CONCLUSION: The current management of the disease includes the use of disease modifying anti-rheumatic drugs and the biologic therapies. Progress in our understanding of RA pathophysiology led to the identification of new therapeutic targets. These include pro-inflammatory cytokines, T and B cells, adhesion molecules, chemokines and intra- and extracellular signaling pathways. Therapeutic modulation of the above targets can provide new treatment strategies. This article reviews a few of the new treatment strategies currently being evaluated. | en |
heal.journalName | Expert Opin Emerg Drugs | en |
heal.journalType | peer-reviewed | - |
heal.fullTextAvailability | TRUE | - |
Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ |
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