Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/21995
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dc.contributor.authorVoulgari, P. V.en
dc.date.accessioned2015-11-24T19:19:54Z-
dc.date.available2015-11-24T19:19:54Z-
dc.identifier.issn1744-7623-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/21995-
dc.rightsDefault Licence-
dc.subjectAnimalsen
dc.subjectAntirheumatic Agents/*therapeutic useen
dc.subjectArthritis, Rheumatoid/*drug therapyen
dc.subjectDrugs, Investigational/*therapeutic useen
dc.subjectHumansen
dc.titleEmerging drugs for rheumatoid arthritisen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1517/14728214.13.1.175-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/18321156-
heal.identifier.secondaryhttp://informahealthcare.com/doi/abs/10.1517/14728214.13.1.175-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2008-
heal.abstractBACKGROUND: Rheumatoid arthritis (RA) is a chronic, inflammatory, systemic, autoimmune disease characterized by symmetric arthritis of diarthrodial joints leading to progressive erosion of cartilage and bone. The individual and social impacts of RA are of great importance. OBJECTIVE: To investigate the development of new therapies for RA treatment. METHODS: Various databases have been searched for new drugs in clinical trials (Phase I - III) and experimental future therapeutic agents for RA. RESULTS/CONCLUSION: The current management of the disease includes the use of disease modifying anti-rheumatic drugs and the biologic therapies. Progress in our understanding of RA pathophysiology led to the identification of new therapeutic targets. These include pro-inflammatory cytokines, T and B cells, adhesion molecules, chemokines and intra- and extracellular signaling pathways. Therapeutic modulation of the above targets can provide new treatment strategies. This article reviews a few of the new treatment strategies currently being evaluated.en
heal.journalNameExpert Opin Emerg Drugsen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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