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https://olympias.lib.uoi.gr/jspui/handle/123456789/21704Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Goussia, A. C. | en |
| dc.contributor.author | Ioachim, E. E. | en |
| dc.contributor.author | Agnantis, N. J. | en |
| dc.contributor.author | Zagorianakou, P. | en |
| dc.contributor.author | Vougiouklakis, T. | en |
| dc.contributor.author | Tsianos, E. V. | en |
| dc.contributor.author | Kappas, A. | en |
| dc.date.accessioned | 2015-11-24T19:16:43Z | - |
| dc.date.available | 2015-11-24T19:16:43Z | - |
| dc.identifier.issn | 0886-3849 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/21704 | - |
| dc.rights | Default Licence | - |
| dc.subject | diffuse-type | en |
| dc.subject | differential expression | en |
| dc.subject | extracellular-matrix | en |
| dc.subject | variant | en |
| dc.subject | isoforms | en |
| dc.subject | intestinal-type | en |
| dc.subject | adenocarcinomas | en |
| dc.subject | progression | en |
| dc.subject | metastasis | en |
| dc.subject | integrins | en |
| dc.subject | carcinoma | en |
| dc.title | Expression of cell adhesion molecule CD44 in human gastric cancer. A correlation with P53 and Rb proteins, the HLA-DR antigen and the proliferative activity | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.secondary | <Go to ISI>://WOS:000087559500006 | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 2000 | - |
| heal.abstract | The expression of the CD44 standard (CD44s) was examined immunohistochemically in a series of 61 gastric adenocarcinomas and analyzed the relation with the expression of HLA-DR antigen, the p53 and Rb protein expression, the proliferation indices Ki-67 and PCNA as well as with conventional clinicopathological variables. CD44s immunoreactivity was detected in 47.6% of the cases. The incidence of CD44s expression did not differ among histological types of carcinomas. CD44s expression was significantly related to depth of invasion (p=0.03) and to Ki-67 positive rate (p=0.018). A trend for correlation with vessel invasion was also observed (p=0.06). The relation of CD44 expression with the other studied variables was insignificant. These data suggest that CD44s may have a major role as adhesion molecule in the progression of gastric carcinomas. In addition, the expression of CD44s is associated with proliferation, suggesting that in gastric cancer CD44s may have a role in tumor cell growth. | en |
| heal.journalName | Journal of Tumor Marker Oncology | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
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