Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/21586
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dc.contributor.authorThilaganathan, B.en
dc.contributor.authorCarroll, S. G.en
dc.contributor.authorPlachouras, N.en
dc.contributor.authorMakrydimas, G.en
dc.contributor.authorNicolaides, K. H.en
dc.date.accessioned2015-11-24T19:15:55Z-
dc.date.available2015-11-24T19:15:55Z-
dc.identifier.issn0306-5456-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/21586-
dc.rightsDefault Licence-
dc.subjectBacterial Infections/blood/*immunologyen
dc.subjectCD4-CD8 Ratioen
dc.subjectFemaleen
dc.subjectFetal Blooden
dc.subjectFetal Diseases/blood/*immunologyen
dc.subjectHumansen
dc.subjectKiller Cells, Natural/*immunologyen
dc.subjectLeukocyte Counten
dc.subjectNeutropenia/etiologyen
dc.subjectPlatelet Counten
dc.subjectPregnancyen
dc.subjectPregnancy Complications, Infectious/*immunologyen
dc.subjectThrombocytopenia/etiologyen
dc.subjectVirus Diseases/blood/*immunologyen
dc.titleFetal immunological and haematological changes in intrauterine infectionen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/8018614-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate1994-
heal.abstractOBJECTIVE: To study fetal immunological and haematological changes to intrauterine infection. DESIGN: In 37 pregnancies at risk of intrauterine infection, fetal blood obtained by cordocentesis at 20 to 36 weeks gestation was used for differential leucocyte counts, platelet count, enumeration of lymphocyte subpopulations, and neutrophil adhesion receptor expression. SETTING: Harris Birthright Research Centre for Fetal Medicine, London. RESULTS: All four fetuses with viral infections had platelet counts below the 5th centile and three had natural killer (NK) cell counts greater than the 95th centile of the normal range. Similarly, all five fetuses with bacterial or candidal infection had neutrophil counts greater than the 95th centile of the normal range; lymphocyte subpopulations were normal. CONCLUSIONS: In pregnancies complicated by intrauterine infection, fetuses exhibit NK cell lymphocytosis and thrombocytopenia in response to viraemia, and neutrophilia in response to bacteraemia from at least 21 weeks gestation.en
heal.journalNameBr J Obstet Gynaecolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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