Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/21531
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dc.contributor.authorRadsak, K. D.en
dc.contributor.authorBrucher, K. H.en
dc.contributor.authorGeorgatos, S. D.en
dc.date.accessioned2015-11-24T19:15:33Z-
dc.date.available2015-11-24T19:15:33Z-
dc.identifier.issn0171-9335-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/21531-
dc.rightsDefault Licence-
dc.subjectAlkaline Phosphatase/metabolismen
dc.subjectCell Nucleus/metabolism/*microbiology/ultrastructureen
dc.subjectCells, Cultureden
dc.subjectCytomegalovirus/*physiology/ultrastructureen
dc.subjectCytopathogenic Effect, Viral/physiologyen
dc.subjectFibroblastsen
dc.subjectHumansen
dc.subjectLamin Type Aen
dc.subjectLaminsen
dc.subjectMicroscopy, Electronen
dc.subjectNuclear Envelope/*ultrastructureen
dc.subjectNuclear Proteins/immunology/*metabolismen
dc.subjectPhosphorylationen
dc.subjectVirus Replication/physiologyen
dc.titleFocal nuclear envelope lesions and specific nuclear lamin A/C dephosphorylation during infection with human cytomegalovirusen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/1652444-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate1991-
heal.abstractMorphological analysis of cytomegalovirus-infected human fibroblasts reveals characteristic alterations of the nuclear envelope during budding of the nucleocapsids from the nucleus. These changes include focal nuclear lamina thickening and formation of "blebs" at the nuclear membranes. Using a specific monoclonal antibody that recognizes a phosphorylated epitope in nuclear lamins A/C, we show here that the cytopathological alterations at the neighborhood of the nuclear lamina are paralleled by a process of systemic dephosphorylation of the nuclear lamins.en
heal.journalNameEur J Cell Biolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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