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https://olympias.lib.uoi.gr/jspui/handle/123456789/21484Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Tsanadis, G. | en |
| dc.contributor.author | Sotiriadis, A. | en |
| dc.contributor.author | Vezyraki, P. | en |
| dc.contributor.author | Kalfakakou, V. | en |
| dc.contributor.author | Zikopoulos, K. | en |
| dc.contributor.author | Dalkahtsis, N. | en |
| dc.contributor.author | Evangelou, A. | en |
| dc.contributor.author | Stefos, T. | en |
| dc.date.accessioned | 2015-11-24T19:15:15Z | - |
| dc.date.available | 2015-11-24T19:15:15Z | - |
| dc.identifier.issn | 0271-5317 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/21484 | - |
| dc.rights | Default Licence | - |
| dc.subject | wistar rats | en |
| dc.subject | copper | en |
| dc.subject | d-penicillamine | en |
| dc.subject | zinc | en |
| dc.subject | fsh | en |
| dc.subject | t3 | en |
| dc.subject | t4 | en |
| dc.subject | tsh | en |
| dc.subject | thyroid-hormone metabolism | en |
| dc.subject | selenium | en |
| dc.subject | deficiency | en |
| dc.subject | pituitary | en |
| dc.subject | complexes | en |
| dc.subject | serum | en |
| dc.title | FSH, TSH, T3 and T4 changes in relation to plasma copper and zinc alterations during D-penicillamine administration in female Wistar rats | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.secondary | <Go to ISI>://000180640900013 | - |
| heal.identifier.secondary | http://ac.els-cdn.com/S0271531702004803/1-s2.0-S0271531702004803-main.pdf?_tid=c0c13b1b65dd30e3658cde7b51ed382c&acdnat=1332741911_84f241a683a1d872779f4e29ec730770 | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 2003 | - |
| heal.abstract | Zinc and copper are considered to antagonize each other in several organs, while they play a significant role in the regulation and function of many systems. D-penicillamine was administered to 19 female Wistar rats for 68 days, 1 g/d/kg B.W. Plasma copper and zinc levels, as well as serum T3, T4, TSH and FSH were measured at days 50, 53, 54, 58, 62 and 68. Copper concentration presented a significant decrease. Zinc showed an initial increase by day 54, followed by a subsequent decrease. FSH levels decreased, presenting a pattern identical with that of copper. T3 and -especially- T4 alterations were similar to that of zinc and copper, whereas TSH alterations were inverse to them. it is concluded that copper and zinc alterations, induced by d-penicillamine administration, can significantly affect pituitary sex hormones (TSH) and hypothalamic-pituitary-thyroid axis in rats. (C) 2003 Elsevier Science Inc. All rights reserved. | en |
| heal.journalName | Nutrition Research | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Tsanadis-2003-FSH, TSH, T3 and T4.pdf | 90.58 kB | Adobe PDF | View/Open Request a copy |
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