Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/21467
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dc.contributor.authorPanoulas, V. F.en
dc.contributor.authorDouglas, K. M.en
dc.contributor.authorSmith, J. P.en
dc.contributor.authorMetsios, G. S.en
dc.contributor.authorElisaf, M. S.en
dc.contributor.authorNightingale, P.en
dc.contributor.authorKitas, G. D.en
dc.date.accessioned2015-11-24T19:15:10Z-
dc.date.available2015-11-24T19:15:10Z-
dc.identifier.issn1525-6006-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/21467-
dc.rightsDefault Licence-
dc.subjectAgeden
dc.subjectArthritis, Rheumatoid/complications/*geneticsen
dc.subjectBlood Pressureen
dc.subjectFemaleen
dc.subjectGalectin 2/*geneticsen
dc.subjectGenotypeen
dc.subjectHumansen
dc.subjectHypertension/complications/*geneticsen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectMyocardial Infarction/complications/*geneticsen
dc.subject*Polymorphism, Single Nucleotideen
dc.subjectPrevalenceen
dc.subjectRisk Factorsen
dc.titleGalectin-2 (LGALS2) 3279C/T polymorphism may be independently associated with diastolic blood pressure in patients with rheumatoid arthritisen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1080/10641960802621267-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/19330599-
heal.identifier.secondaryhttp://informahealthcare.com/doi/abs/10.1080/10641960802621267-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2009-
heal.abstractThe galectin-2 (LGALS2) 3279 C/T single nucleotide polymorphism (SNP) has recently been associated with myocardial infarction (MI). Although hypertension, a very prevalent entity in rheumatoid arthritis (RA), is one of the greatest risk factors for MI, the possible association of LGALS2 3279 C/T and hypertension has not been investigated. We genotyped 386 RA patients, 272 hypertensives and 114 normotensives. Diastolic blood pressure (DBP) was significantly lower in TT compared to CC homozygotes (-4.11 mmHg, p = 0.044) even when adjusted for multiple confounders (-4.28 mmHg, p = 033). Further studies are required to replicate the potential association of LGALS2 3279 C/T with DBP, and examine whether this SNP could be used as a marker of increased risk for future cardiovascular events in RA populations.en
heal.journalNameClin Exp Hypertensen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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