Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/21446
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dc.contributor.authorJawaheer, D.en
dc.contributor.authorOlsen, J.en
dc.contributor.authorLahiff, M.en
dc.contributor.authorForsberg, S.en
dc.contributor.authorLahteenmaki, J.en
dc.contributor.authorda Silveira, I. G.en
dc.contributor.authorRocha, F. A.en
dc.contributor.authorMagalhaes Laurindo, I. M.en
dc.contributor.authorHenrique da Mota, L. M.en
dc.contributor.authorDrosos, A. A.en
dc.contributor.authorMurphy, E.en
dc.contributor.authorSheehy, C.en
dc.contributor.authorQuirke, E.en
dc.contributor.authorCutolo, M.en
dc.contributor.authorRexhepi, S.en
dc.contributor.authorDadoniene, J.en
dc.contributor.authorVerstappen, S. M.en
dc.contributor.authorSokka, T.en
dc.date.accessioned2015-11-24T19:15:04Z-
dc.date.available2015-11-24T19:15:04Z-
dc.identifier.issn0392-856X-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/21446-
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectAgeden
dc.subjectArthritis, Rheumatoid/*physiopathologyen
dc.subject*Body Mass Indexen
dc.subjectDisability Evaluationen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectLinear Modelsen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectRetrospective Studiesen
dc.subjectSelf Disclosureen
dc.subject*Severity of Illness Indexen
dc.subject*Sex Characteristicsen
dc.titleGender, body mass index and rheumatoid arthritis disease activity: results from the QUEST-RA Studyen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/20810033-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2010-
heal.abstractOBJECTIVES: To investigate whether body mass index (BMI), as a proxy for body fat, influences rheumatoid arthritis (RA) disease activity in a gender-specific manner. METHODS: Consecutive patients with RA were enrolled from 25 countries into the QUEST-RA program between 2005 and 2008. Clinical and demographic data were collected by treating rheumatologists and by patient self-report. Distributions of Disease Activity Scores (DAS28), BMI, age, and disease duration were assessed for each country and for the entire dataset; mean values between genders were compared using Student's t-tests. An association between BMI and DAS28 was investigated using linear regression, adjusting for age, disease duration and country. RESULTS: A total of 5,161 RA patients (4,082 women and 1,079 men) were included in the analyses. Overall, women were younger, had longer disease duration, and higher DAS28 scores than men, but BMI was similar between genders. The mean DAS28 scores increased with increasing BMI from normal to overweight and obese, among women, whereas the opposite trend was observed among men. Regression results showed BMI (continuous or categorical) to be associated with DAS28. Compared to the normal BMI range, being obese was associated with a larger difference in mean DAS28 (0.23, 95% CI: 0.11, 0.34) than being overweight (0.12, 95% CI: 0.03, 0.21); being underweight was not associated with disease activity. These associations were more pronounced among women, and were not explained by any single component of the DAS28. CONCLUSIONS: BMI appears to be associated with RA disease activity in women, but not in men.en
heal.journalNameClin Exp Rheumatolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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